Tan Lab | DSigDB

Gene Set: D4 : CTD - Ellagic Acid

Collection

D4 : CTD

Chemical Name

Ellagic Acid ( From PubChem : ELLAGIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
302.193 g/mol	4	8	1.3128	True

Structure

InChI

InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

InChIKey

AFSDNFLWKVMVRB-UHFFFAOYSA-N

Links

Gene (146 / 211)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ACPP		D004610
CTD	increases(activity)			ALB		D004610
CTD	increases(reaction)			ALB		D004610
CTD	decreases(expression)			APAF1		D004610
CTD	increases(expression)			ASCL1		D004610
CTD	increases(expression)			ASNS		D004610
CTD	increases(expression)			ATF3		D004610
CTD	increases(expression)			ATG5		D004610
CTD	increases(expression)			BCL2		D004610
CTD	decreases(expression)			BMP6		D004610
CTD	decreases(expression)			BRF1		D004610
CTD	decreases(expression)			CALR		D004610
CTD	decreases(activity)			CASP3		D004610
CTD	decreases(expression)			CASP3		D004610
CTD	increases(activity)			CASP3		D004610
CTD	increases(expression)			CASP3		D004610
CTD	decreases(secretion)			CCL2		D004610
CTD	decreases(expression)			CD14		D004610
CTD	decreases(reaction)			CXCL8		D004610
CTD	increases(secretion)			CXCL8		D004610
CTD	decreases(expression)			CYP1A1		D004610
CTD	decreases(expression)			DAXX		D004610
CTD	decreases(expression)			DFFA		D004610
CTD	increases(expression)			E4F1		D004610
CTD	decreases(expression)			EGR3		D004610
CTD	increases(expression)			EP300		D004610
CTD	increases(expression)			EPS15		D004610
CTD	increases(expression)			EZH1		D004610
CTD	increases(activity)			F12		D004610
CTD	increases(reaction)			F12		D004610
CTD	decreases(expression)			FGFR1		D004610
CTD	decreases(expression)			FLNA		D004610
CTD	decreases(expression)			GPLD1		D004610
CTD	increases(expression)			GSTA4		D004610
CTD	increases(expression)			GTF2E2		D004610
CTD	increases(expression)			GTF2H4		D004610
CTD	decreases(expression)			HIF1A		D004610
CTD	increases(expression)			HMOX1		D004610
CTD	increases(expression)			IER2		D004610
CTD	increases(expression)			IGFBP2		D004610
CTD	decreases(expression)			IGFBP4		D004610
CTD	decreases(reaction)			IL1B		D004610
CTD	increases(secretion)			IL1B		D004610
CTD	decreases(expression)			IL1B		D004610
CTD	decreases(expression)			IL1R1		D004610
CTD	increases(expression)			INPP5D		D004610
CTD	increases(expression)			IQGAP2		D004610
CTD	increases(expression)			IRF9		D004610
CTD	decreases(expression)			JUN		D004610
CTD	decreases(expression)			KLK3		D004610
CTD	increases(expression)			LITAF		D004610
CTD	decreases(expression)			MAP1A		D004610
CTD	decreases(expression)			MAP3K1		D004610
CTD	increases(expression)			MAPK11		D004610
CTD	increases(expression)			MMD		D004610
CTD	decreases(activity)			MMP2		D004610
CTD	decreases(secretion)			MMP2		D004610
CTD	decreases(reaction)			MMP2		D004610
CTD	affects(localization)			NFE2L2		D004610
CTD	increases(expression)			NFE2L2		D004610
CTD	affects(response to substance)			NFE2L2		D004610
CTD	decreases(expression)			NFKB2		D004610
CTD	increases(expression)			NNAT		D004610
CTD	decreases(expression)			NOP56		D004610
CTD	increases(expression)			NPAS2		D004610
CTD	increases(activity)			NR1I3		D004610
CTD	decreases(activity)			PARG		D004610
CTD	decreases(expression)			PLA2G2A		D004610
CTD	increases(expression)			PLP2		D004610
CTD	decreases(expression)			PML		D004610
CTD	decreases(expression)			PPARD		D004610
CTD	increases(expression)			PPARG		D004610
CTD	decreases(expression)			PRKG1		D004610
CTD	decreases(expression)			PTN		D004610
CTD	increases(expression)			PTN		D004610
CTD	increases(expression)			PTPRN2		D004610
CTD	decreases(expression)			RAN		D004610
CTD	increases(expression)			RECK		D004610
CTD	decreases(reaction)			RECK		D004610
CTD	decreases(expression)			RELA		D004610
CTD	decreases(expression)			RGS5		D004610
CTD	decreases(expression)			SCD		D004610
CTD	increases(expression)			SEPT2		D004610
CTD	decreases(expression)			SOD3		D004610
CTD	decreases(expression)			STAT3		D004610
CTD	increases(expression)			STAT3		D004610
CTD	decreases(expression)			TAF1C		D004610
CTD	increases(expression)			TCF12		D004610
CTD	decreases(reaction)			TERT		D004610
CTD	increases(expression)			TERT		D004610
CTD	decreases(expression)			TFAM		D004610
CTD	increases(expression)			TGFB1		D004610
CTD	decreases(expression)			UGP2		D004610
CTD	decreases(expression)			USP4		D004610
CTD	increases(expression)			WARS		D004610
CTD	decreases(expression)			ZBTB16		D004610
CTD	increases(expression)			ZMYM2		D004610
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	None	uM		ADRBK1	-	GI(Protien) :
PubChem	Average IC50	uM	0.450	APOBEC3G	-	GI(Protien) :
PubChem	Potency	uM	0.794	BAZ2B	-	GI(Protien) :
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	Potency	uM	1.122	BLM	-	GI(Protien) :
PubChem	Potency	uM	1.995	BLM	-	GI(Protien) :
PubChem	Potency	uM	15.849	BLM	-	GI(Protien) :
PubChem	Potency	uM	0.159	CBFB	-	GI(Protien) :
PubChem	None	uM		CTDSP1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP2C19	-	GI(Protien) :
PubChem	None	uM		DLD	-	GI(Protien) :
PubChem	None	uM		DNMT1	-	GI(Protien) :
PubChem	Potency	uM	1.259	EHMT2	-	GI(Protien) :
PubChem	None	uM		EIF4G1	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	None	uM		ESR2	-	GI(Protien) :
PubChem	None	uM		FASN	-	GI(Protien) :
PubChem	Potency	uM	1.585	FEN1	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	2.818	GLS	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		GNAO1	-	GI(Protien) :
PubChem	None	uM		GNAO1	-	GI(Protien) :
PubChem	None	uM		GNAO1	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Potency	uM	10.000	HBB	-	GI(Protien) :
PubChem	None	uM		HKDC1	-	GI(Protien) :
PubChem	Potency	uM	0.126	HPGD	-	GI(Protien) :
PubChem	Potency	uM	0.891	HPGD	-	GI(Protien) :
PubChem	IC50	uM	0.760	HSPA1A	-	GI(Protien) :
PubChem	IC50	uM	99.200	HSPA8	-	GI(Protien) :
PubChem	IC50	uM	99.200	HSPA8	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	19.953	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	12.589	MAPT	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	31.623	MAPT	-	GI(Protien) :
PubChem	Absolute IC50	uM	0.570	MCL1	-	GI(Protien) :
PubChem	IC50	uM	54.000	MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	IC50	uM		MPI	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		PAFAH1B2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B3	-	GI(Protien) :
PubChem	None	uM		PAFAH2	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	8.437	PLK1	-	GI(Protien) :
PubChem	Potency	uM	0.159	POLB	-	GI(Protien) :
PubChem	Potency	uM	0.794	POLH	-	GI(Protien) :
PubChem	Potency	uM	0.100	POLI	-	GI(Protien) :
PubChem	Potency	uM	1.122	POLI	-	GI(Protien) :
PubChem	Potency	uM	0.126	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.251	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.794	POLK	-	GI(Protien) :
PubChem	None	uM		PPP1CA	-	GI(Protien) :
PubChem	None	uM		PREPL	-	GI(Protien) :
PubChem	None	uM		PTPN5	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	None	uM		RGS7	-	GI(Protien) :
PubChem	None	uM		RGS8	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	Potency	uM	0.159	RUNX1	-	GI(Protien) :
PubChem	None	uM		SIX1	-	GI(Protien) :
PubChem	IC50	uM	0.142	SMAD3	-	GI(Protien) :
PubChem	None	uM		SMAD3	-	GI(Protien) :
PubChem	None	uM		SUMO1	-	GI(Protien) :
PubChem	None	uM		TNNC1	-	GI(Protien) :
PubChem	None	uM		TNNI3	-	GI(Protien) :
PubChem	None	uM		TNNT2	-	GI(Protien) :
PubChem	Potency	uM	1.122	USP2	-	GI(Protien) :
PubChem	Potency	uM	39.811	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	11.200	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	14.100	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	44.700	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	794.300	BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Potency	nM	1995.300	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	1122.000	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	15848.900	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	158.500	CBFB	-	Target : CHEMBL2093862
ChEMBL	Potency	nM	31622.800	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	1258.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	10000.000	HBB	-	Target : CHEMBL4331
ChEMBL	Potency	nM	891.300	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	125.900	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	251.200	HSD17B10	-	Target : CHEMBL4159
ChEMBL	IC50	nM	760.000	HSPA1A; HSPA1B	-	Target : CHEMBL5460
ChEMBL	IC50	nM	99200.000	HSPA8	-	Target : CHEMBL1275223
ChEMBL	Potency	nM	707.900	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	794.300	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	2511.900	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	7079.500	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	19952.600	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	31622.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	12589.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224
ChEMBL	IC50	nM	54000.000	MCL1	-	Target : CHEMBL4361
ChEMBL	Potency	nM	158.500	POLB	-	Target : CHEMBL2392
ChEMBL	Potency	nM	562.300	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	125.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	158.500	RUNX1	-	Target : CHEMBL2093862
ChEMBL	IC50	nM	142.000	SMAD3	-	Target : CHEMBL1293258
ChEMBL	Potency	nM	70.800	TDP1	-	Target : CHEMBL1075138
ChEMBL	Potency	nM	4.000	TDP1	-	Target : CHEMBL1075138
ChEMBL	Potency	nM	100.000	TDP1	-	Target : CHEMBL1075138
ChEMBL	Potency	nM	1122.000	USP2	-	Target : CHEMBL1293227

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