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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Edetic Acid

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Collection	D4 : CTD
Chemical Name	Edetic Acid ( From PubChem : EDTA )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Approved Approved Approved Approved Approved Approved Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 292.243 g/mol 4 10 -2.0712 True
Structure
InChI	InChI=1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
InChIKey	KCXVZYZYPLLWCC-UHFFFAOYSA-N
Links
Gene (17 / 36) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(activity) ANPEP D004492 CTD increases(reaction) ANPEP D004492 CTD affects(binding) APP D004492 CTD affects(cotreatment) APP D004492 CTD decreases(reaction) APP D004492 CTD increases(chemical synthesis) APP D004492 CTD increases(oxidation) APP D004492 CTD decreases(activity) ASPA D004492 CTD affects(binding) BMP4 D004492 CTD decreases(reaction) BMP4 D004492 CTD decreases(reaction) CYP2E1 D004492 CTD increases(degradation) CYP2E1 D004492 CTD decreases(phosphorylation) DUSP23 D004492 CTD decreases(reaction) DUSP23 D004492 CTD decreases(activity) ENPP7 D004492 CTD decreases(reaction) ENPP7 D004492 CTD increases(expression) ESR1 D004492 CTD decreases(reaction) IL6 D004492 CTD increases(expression) IL6 D004492 CTD increases(reaction) IL6 D004492 CTD increases(expression) ITGAM D004492 CTD affects(binding) MGP D004492 CTD decreases(reaction) MGP D004492 CTD decreases(activity) MMP8 D004492 CTD increases(alkylation) MT3 D004492 CTD affects(metabolic processing) MT3 D004492 CTD affects(binding) NEIL1 D004492 CTD decreases(activity) NEIL1 D004492 CTD decreases(reaction) NEIL1 D004492 CTD affects(cotreatment) NEIL1 D004492 CTD decreases(expression) SELL D004492 CTD decreases(reaction) TRPV1 D004492 CTD increases(reaction) TRPV1 D004492 CTD increases(uptake) TRPV1 D004492 CTD increases(activity) TXNRD1 D004492 CTD decreases(reaction) TXNRD1 D004492
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