Tan Lab | DSigDB

Gene Set: D4 : CTD - Dydrogesterone

Collection

D4 : CTD

Chemical Name

Dydrogesterone ( From PubChem : DYDROGESTERONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
312.446 g/mol	0	2	4.4995	True

Structure

InChI

InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20+,21+/m0/s1

InChIKey

Links

Gene (16 / 36)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(metabolic processing)			AKR1C1		D004394
CTD	decreases(activity)			AKR1C1		D004394
CTD	decreases(expression)			AKR1C1		D004394
CTD	increases(expression)			AKR1C1		D004394
CTD	decreases(activity)			AKR1C2		D004394
CTD	decreases(expression)			AKR1C2		D004394
CTD	decreases(activity)			AKR1C3		D004394
CTD	decreases(expression)			AKR1C3		D004394
CTD	affects(reaction)			EDN1		D004394
CTD	decreases(expression)			EDN1		D004394
CTD	decreases(expression)			HSD17B2		D004394
CTD	increases(expression)			HSD17B2		D004394
CTD	decreases(expression)			IFNG		D004394
CTD	decreases(reaction)			IFNG		D004394
CTD	increases(expression)			IL4		D004394
CTD	decreases(reaction)			IL4		D004394
CTD	increases(expression)			IL6		D004394
CTD	decreases(reaction)			IL6		D004394
CTD	affects(activity)			PGR		D004394
CTD	decreases(expression)			PGR		D004394
CTD	affects(expression)			PIBF1		D004394
CTD	increases(expression)			PIBF1		D004394
CTD	decreases(expression)			SRD5A1		D004394
CTD	decreases(expression)			TNF		D004394
CTD	decreases(reaction)			TNF		D004394
PubChem	Ratio Potency (uM)	uM	0.204	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.439	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.023	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.332	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	18.832	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.775	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.816	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.570	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.995	TDP1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :

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