Tan Lab | DSigDB

Gene Set: D4 : CTD - tetraiodothyroacetic acid

Collection

D4 : CTD

Chemical Name

tetraiodothyroacetic acid ( From PubChem : TETRAC )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
747.829 g/mol	2	4	5.23	False(2/4)

Structure

InChI

InChI=1S/C14H8I4O4/c15-8-4-7(5-9(16)13(8)21)22-14-10(17)1-6(2-11(14)18)3-12(19)20/h1-2,4-5,21H,3H2,(H,19,20)

InChIKey

Links

Gene (10 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			MAPK1		C011126
CTD	increases(activity)			MAPK1		C011126
CTD	increases(phosphorylation)			MAPK1		C011126
CTD	decreases(reaction)			MAPK3		C011126
CTD	increases(activity)			MAPK3		C011126
CTD	increases(phosphorylation)			MAPK3		C011126
CTD	affects(binding)			NCOR1		C011126
CTD	decreases(reaction)			NCOR1		C011126
CTD	affects(binding)			NCOR2		C011126
CTD	decreases(reaction)			NCOR2		C011126
CTD	affects(binding)			THRB		C011126
CTD	decreases(reaction)			THRB		C011126
PubChem	Potency-Replicate_1	uM	15.179	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	24.057	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.410	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.992	NR1H4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	26.992	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.746	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

Download gene sets