Tan Lab | DSigDB

Gene Set: D4 : CTD - Dihydroxyphenylalanine

Collection

D4 : CTD

Chemical Name

Dihydroxyphenylalanine ( From PubChem : DL-DOPA )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
197.188 g/mol	4	5	0.7525	True

Structure

InChI

InChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChIKey

Links

Gene (12 / 24)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(reaction)			SULT1A3		D004295
CTD	increases(sulfation)			SULT1A3		D004295
PubChem	Potency	uM	3.981	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	8.912	BLM	-	GI(Protien) :
PubChem	Potency	uM	0.891	CBFB	-	GI(Protien) :
PubChem	Potency	uM	1.122	CBFB	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	11.220	MAPT	-	GI(Protien) :
PubChem	Potency	uM	25.119	MAPT	-	GI(Protien) :
PubChem	Potency	uM	0.159	POLK	-	GI(Protien) :
PubChem	Potency	uM	0.891	RUNX1	-	GI(Protien) :
PubChem	Potency	uM	1.122	RUNX1	-	GI(Protien) :
PubChem	Potency	uM	2.909	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.663	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	3981.100	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	158.500	APEX1	-	Target : CHEMBL5619
ChEMBL	Potency	nM	8912.500	BLM	-	Target : CHEMBL1293237
ChEMBL	Potency	nM	1122.000	CBFB	-	Target : CHEMBL2093862
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	17782.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	25118.900	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	11220.200	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	2511.900	RECQL	-	Target : CHEMBL1293236
ChEMBL	Potency	nM	1122.000	RUNX1	-	Target : CHEMBL2093862

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