Tan Lab | DSigDB

Gene Set: D4 : CTD - Dimethylphenylpiperazinium Iodide

Collection

D4 : CTD

Chemical Name

Dimethylphenylpiperazinium Iodide ( From PubChem : DMPP )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
318.197 g/mol	0	1	-1.3892	True

Structure

InChI

InChI=1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1

InChIKey

Links

Gene (12 / 31)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			CHRNA2		D004246
CTD	increases(activity)			CHRNA2		D004246
CTD	affects(binding)			CHRNA3		D004246
CTD	increases(activity)			CHRNA3		D004246
CTD	affects(binding)			CHRNA4		D004246
CTD	decreases(reaction)			CHRNA4		D004246
CTD	increases(activity)			CHRNA4		D004246
CTD	affects(binding)			CHRNA4		D004246
CTD	increases(activity)			CHRNA4		D004246
CTD	increases(response to substance)			CHRNA7		D004246
CTD	affects(binding)			CHRNA7		D004246
CTD	decreases(reaction)			CHRNA7		D004246
CTD	increases(activity)			CHRNA7		D004246
CTD	affects(binding)			CHRNB2		D004246
CTD	decreases(reaction)			CHRNB2		D004246
CTD	increases(activity)			CHRNB2		D004246
CTD	affects(binding)			CHRNB4		D004246
CTD	increases(activity)			CHRNB4		D004246
PubChem	IC50_Mean	uM	1.930	APOBEC3A	-	GI(Protien) :
PubChem	None	uM		APOBEC3A	-	GI(Protien) :
PubChem	None	uM		APOBEC3A	-	GI(Protien) :
PubChem	IC50	uM	2.620	APOBEC3G	-	GI(Protien) :
PubChem	Potency	uM	0.631	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	12.589	EHMT2	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
ChEMBL	IC50	nM	1930.000	APOBEC3A	-	Target : CHEMBL1741179
ChEMBL	IC50	nM	2620.000	APOBEC3G	-	Target : CHEMBL1741217
ChEMBL	Potency	nM	631.000	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	12589.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	44668.400	KDM4A	-	Target : CHEMBL5896

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