Tan Lab | DSigDB

Gene Set: D4 : CTD - Dinitrochlorobenzene

Collection

D4 : CTD

Chemical Name

Dinitrochlorobenzene ( From PubChem : 1-CHLORO-2,4-DINITROBENZENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
202.552 g/mol	0	0	3.2028	True

Structure

InChI

InChI=1S/C6H3ClN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChIKey

VYZAHLCBVHPDDF-UHFFFAOYSA-N

Links

Gene (242 / 320)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCA6		D004137
CTD	decreases(expression)			ABHD10		D004137
CTD	increases(expression)			ACOX2		D004137
CTD	increases(expression)			ADORA2B		D004137
CTD	increases(expression)			AKR1B1		D004137
CTD	increases(expression)			AKR1B10		D004137
CTD	increases(expression)			AKR1C1		D004137
CTD	increases(activity)			AKR1C2		D004137
CTD	increases(expression)			AKR1C2		D004137
CTD	increases(expression)			AKR1C3		D004137
CTD	increases(expression)			ANXA1		D004137
CTD	increases(expression)			ANXA2		D004137
CTD	increases(expression)			ARG2		D004137
CTD	increases(expression)			ARL4C		D004137
CTD	increases(expression)			ATF3		D004137
CTD	decreases(expression)			AZIN1		D004137
CTD	increases(expression)			BAMBI		D004137
CTD	decreases(expression)			BCLAF1		D004137
CTD	increases(expression)			BMP6		D004137
CTD	increases(expression)			BTG1		D004137
CTD	decreases(expression)			BUB1		D004137
CTD	decreases(expression)			C12ORF4		D004137
CTD	decreases(expression)			CA2		D004137
CTD	increases(expression)			CALCA		D004137
CTD	increases(expression)			CALCRL		D004137
CTD	increases(expression)			CAT		D004137
CTD	decreases(expression)			CCL2		D004137
CTD	decreases(secretion)			CCL2		D004137
CTD	increases(expression)			CCL2		D004137
CTD	increases(secretion)			CCL2		D004137
CTD	increases(expression)			CCL3		D004137
CTD	increases(expression)			CCL4		D004137
CTD	increases(expression)			CCL4		D004137
CTD	increases(secretion)			CCL4		D004137
CTD	increases(secretion)			CCL5		D004137
CTD	decreases(expression)			CCR2		D004137
CTD	increases(expression)			CCR2		D004137
CTD	increases(expression)			CCR5		D004137
CTD	decreases(expression)			CCR7		D004137
CTD	increases(expression)			CCR7		D004137
CTD	increases(expression)			CCR7		D004137
CTD	affects(reaction)			CCR7		D004137
CTD	increases(expression)			CCR7		D004137
CTD	increases(expression)			CD274		D004137
CTD	decreases(expression)			CD36		D004137
CTD	increases(expression)			CD40		D004137
CTD	increases(expression)			CD83		D004137
CTD	decreases(reaction)			CD86		D004137
CTD	increases(expression)			CD86		D004137
CTD	decreases(reaction)			CD86		D004137
CTD	increases(expression)			CD86		D004137
CTD	decreases(reaction)			CD86		D004137
CTD	increases(expression)			CD86		D004137
CTD	increases(expression)			CD86		D004137
CTD	increases(expression)			CD86		D004137
CTD	decreases(expression)			CDH8		D004137
CTD	increases(expression)			CDKN1A		D004137
CTD	increases(expression)			CDKN1C		D004137
CTD	decreases(expression)			CERKL		D004137
CTD	increases(expression)			CES1		D004137
CTD	increases(expression)			CIDEC		D004137
CTD	decreases(expression)			CISD1		D004137
CTD	increases(expression)			CLIC4		D004137
CTD	decreases(expression)			CMPK2		D004137
CTD	decreases(expression)			CPNE3		D004137
CTD	affects(expression)			CREB1		D004137
CTD	increases(expression)			CREM		D004137
CTD	increases(expression)			CTSB		D004137
CTD	decreases(expression)			CTSC		D004137
CTD	increases(expression)			CTSL		D004137
CTD	increases(expression)			CXCL1		D004137
CTD	increases(expression)			CXCL10		D004137
CTD	increases(expression)			CXCL2		D004137
CTD	decreases(reaction)			CXCL8		D004137
CTD	increases(secretion)			CXCL8		D004137
CTD	affects(reaction)			CXCL8		D004137
CTD	increases(expression)			CXCL8		D004137
CTD	increases(expression)			CXCL8		D004137
CTD	increases(secretion)			CXCL8		D004137
CTD	increases(stability)			CXCL8		D004137
CTD	affects(reaction)			CXCL8		D004137
CTD	increases(secretion)			CXCL8		D004137
CTD	decreases(reaction)			CXCL8		D004137
CTD	increases(expression)			CXCL8		D004137
CTD	decreases(expression)			CXCR4		D004137
CTD	increases(expression)			CXCR4		D004137
CTD	increases(expression)			CYP1A1		D004137
CTD	increases(expression)			CYTIP		D004137
CTD	decreases(expression)			DCTPP1		D004137
CTD	increases(expression)			DDIT3		D004137
CTD	decreases(reaction)			DDIT3		D004137
CTD	decreases(expression)			DKC1		D004137
CTD	decreases(expression)			DLGAP5		D004137
CTD	increases(expression)			DNAJB4		D004137
CTD	increases(expression)			DNAJB6		D004137
CTD	decreases(expression)			DPYD		D004137
CTD	decreases(expression)			DSE		D004137
CTD	increases(expression)			DUSP1		D004137
CTD	decreases(expression)			EGF		D004137
CTD	decreases(expression)			EGR2		D004137
CTD	increases(expression)			EHHADH		D004137
CTD	increases(expression)			ELAVL1		D004137
CTD	decreases(expression)			EMB		D004137
CTD	affects(expression)			EMD		D004137
CTD	affects(expression)			ESR1		D004137
CTD	decreases(expression)			F13A1		D004137
CTD	decreases(expression)			FBXO9		D004137
CTD	increases(expression)			FECH		D004137
CTD	increases(expression)			FGF9		D004137
CTD	decreases(expression)			FGL2		D004137
CTD	increases(expression)			FIGF		D004137
CTD	increases(expression)			FOS		D004137
CTD	increases(expression)			FOSL2		D004137
CTD	increases(expression)			FTH1		D004137
CTD	increases(expression)			FTL		D004137
CTD	increases(expression)			G6PD		D004137
CTD	affects(expression)			GAL3ST1		D004137
CTD	increases(expression)			GCLC		D004137
CTD	increases(expression)			GCLM		D004137
CTD	increases(expression)			GPNMB		D004137
CTD	increases(expression)			GPX3		D004137
CTD	increases(expression)			GREM1		D004137
CTD	increases(expression)			GSK3B		D004137
CTD	increases(expression)			GSR		D004137
CTD	affects(cotreatment)			GSTA1		D004137
CTD	affects(metabolic processing)			GSTA1		D004137
CTD	affects(binding)			GSTA1		D004137
CTD	affects(cotreatment)			GSTA1		D004137
CTD	affects(metabolic processing)			GSTA1		D004137
CTD	affects(binding)			GSTA1		D004137
CTD	affects(metabolic processing)			GSTA1		D004137
CTD	increases(metabolic processing)			GSTA1		D004137
CTD	decreases(metabolic processing)			GSTA2		D004137
CTD	increases(metabolic processing)			GSTA2		D004137
CTD	affects(binding)			GSTA4		D004137
CTD	affects(metabolic processing)			GSTA4		D004137
CTD	affects(binding)			GSTM1		D004137
CTD	affects(metabolic processing)			GSTM1		D004137
CTD	affects(metabolic processing)			GSTM2		D004137
CTD	affects(metabolic processing)			GSTM3		D004137
CTD	decreases(metabolic processing)			GSTM3		D004137
CTD	increases(metabolic processing)			GSTM3		D004137
CTD	affects(metabolic processing)			GSTM4		D004137
CTD	affects(cotreatment)			GSTM4		D004137
CTD	affects(metabolic processing)			GSTM4		D004137
CTD	affects(metabolic processing)			GSTP1		D004137
CTD	affects(binding)			GSTP1		D004137
CTD	increases(glutathionylation)			GSTP1		D004137
CTD	decreases(reaction)			GSTP1		D004137
CTD	affects(metabolic processing)			GSTZ1		D004137
CTD	increases(expression)			GTF2B		D004137
CTD	decreases(expression)			GYPB		D004137
CTD	decreases(expression)			HEATR5B		D004137
CTD	increases(expression)			HIPK2		D004137
CTD	decreases(reaction)			HMOX1		D004137
CTD	increases(expression)			HMOX1		D004137
CTD	increases(expression)			HMOX1		D004137
CTD	decreases(expression)			HNRNPA3		D004137
CTD	increases(expression)			HSPA6		D004137
CTD	increases(expression)			ICAM1		D004137
CTD	increases(expression)			ID2		D004137
CTD	decreases(expression)			IDI1		D004137
CTD	increases(expression)			IER3		D004137
CTD	decreases(expression)			IFIT2		D004137
CTD	increases(expression)			IFRD1		D004137
CTD	increases(expression)			IGFBP6		D004137
CTD	affects(expression)			IL1B		D004137
CTD	increases(expression)			IL1B		D004137
CTD	increases(secretion)			IL1B		D004137
CTD	increases(expression)			IL1RL1		D004137
CTD	increases(expression)			IL6		D004137
CTD	increases(expression)			IL7R		D004137
CTD	decreases(expression)			IPCEF1		D004137
CTD	increases(expression)			IRF1		D004137
CTD	increases(expression)			JUN		D004137
CTD	decreases(expression)			KCNJ2		D004137
CTD	decreases(reaction)			KEAP1		D004137
CTD	increases(expression)			KEAP1		D004137
CTD	decreases(expression)			KIF23		D004137
CTD	increases(expression)			KLF6		D004137
CTD	increases(expression)			MAFF		D004137
CTD	increases(expression)			MAFG		D004137
CTD	increases(expression)			MAFK		D004137
CTD	decreases(expression)			MAGEF1		D004137
CTD	decreases(phosphorylation)			MAPK1		D004137
CTD	decreases(reaction)			MAPK1		D004137
CTD	increases(phosphorylation)			MAPK14		D004137
CTD	decreases(phosphorylation)			MAPK3		D004137
CTD	decreases(reaction)			MAPK3		D004137
CTD	increases(phosphorylation)			MAPK8		D004137
CTD	increases(expression)			MARCKS		D004137
CTD	decreases(expression)			MCTS1		D004137
CTD	increases(expression)			ME1		D004137
CTD	affects(binding)			MGMT		D004137
CTD	increases(expression)			MGST1		D004137
CTD	increases(expression)			MMP1		D004137
CTD	increases(expression)			MMP3		D004137
CTD	decreases(expression)			MPO		D004137
CTD	decreases(expression)			MRPL35		D004137
CTD	decreases(expression)			MRPS6		D004137
CTD	increases(expression)			MS4A7		D004137
CTD	increases(expression)			MT1X		D004137
CTD	increases(expression)			MT2A		D004137
CTD	decreases(expression)			MYB		D004137
CTD	decreases(expression)			MYC		D004137
CTD	increases(expression)			NAMPT		D004137
CTD	decreases(reaction)			NFE2L2		D004137
CTD	increases(expression)			NFE2L2		D004137
CTD	increases(expression)			NFE2L2		D004137
CTD	decreases(expression)			NFKB1		D004137
CTD	increases(expression)			NINJ1		D004137
CTD	affects(expression)			NPR3		D004137
CTD	decreases(reaction)			NQO1		D004137
CTD	increases(expression)			NQO1		D004137
CTD	increases(expression)			NQO1		D004137
CTD	increases(expression)			NR0B1		D004137
CTD	increases(expression)			NR3C1		D004137
CTD	decreases(expression)			NREP		D004137
CTD	increases(expression)			NUP88		D004137
CTD	increases(expression)			OTUD1		D004137
CTD	decreases(expression)			PAICS		D004137
CTD	increases(expression)			PDE4B		D004137
CTD	increases(expression)			PDE4D		D004137
CTD	increases(expression)			PGD		D004137
CTD	increases(expression)			PHLDA1		D004137
CTD	increases(expression)			PICALM		D004137
CTD	increases(expression)			PIR		D004137
CTD	increases(expression)			PLAT		D004137
CTD	increases(expression)			PLIN2		D004137
CTD	increases(expression)			PMAIP1		D004137
CTD	affects(oxidation)			PRDX1		D004137
CTD	increases(oxidation)			PRDX2		D004137
CTD	decreases(expression)			PRDX3		D004137
CTD	increases(oxidation)			PRDX3		D004137
CTD	affects(localization)			PRKCB		D004137
CTD	decreases(expression)			PSMA5		D004137
CTD	decreases(expression)			PTGER3		D004137
CTD	increases(expression)			PTGR1		D004137
CTD	increases(expression)			PTGS2		D004137
CTD	decreases(expression)			PYHIN1		D004137
CTD	decreases(expression)			RAB32		D004137
CTD	decreases(expression)			RBM17		D004137
CTD	decreases(expression)			RBPJ		D004137
CTD	increases(expression)			RGS1		D004137
CTD	increases(expression)			RGS2		D004137
CTD	increases(expression)			RHOC		D004137
CTD	increases(expression)			RPL27A		D004137
CTD	increases(expression)			S100A10		D004137
CTD	decreases(expression)			S100B		D004137
CTD	increases(expression)			SAT1		D004137
CTD	increases(expression)			SDC2		D004137
CTD	increases(expression)			SEMA4C		D004137
CTD	decreases(expression)			SERBP1		D004137
CTD	increases(expression)			SI		D004137
CTD	decreases(expression)			SLAMF1		D004137
CTD	decreases(expression)			SLAMF8		D004137
CTD	increases(expression)			SLC16A10		D004137
CTD	decreases(expression)			SLC2A3		D004137
CTD	increases(expression)			SLC2A3		D004137
CTD	increases(expression)			SLC7A5		D004137
CTD	decreases(expression)			SMC1A		D004137
CTD	increases(expression)			SNAI1		D004137
CTD	increases(expression)			SNX9		D004137
CTD	increases(expression)			SOD1		D004137
CTD	increases(expression)			SOD2		D004137
CTD	increases(expression)			SOD3		D004137
CTD	increases(expression)			SPTA1		D004137
CTD	decreases(expression)			SRP72		D004137
CTD	increases(expression)			SRXN1		D004137
CTD	decreases(expression)			STAT1		D004137
CTD	increases(expression)			STAT4		D004137
CTD	increases(expression)			STAT5B		D004137
CTD	increases(expression)			STX11		D004137
CTD	increases(expression)			TGIF1		D004137
CTD	increases(expression)			TIMP3		D004137
CTD	affects(expression)			TNF		D004137
CTD	increases(secretion)			TNF		D004137
CTD	affects(reaction)			TNF		D004137
CTD	increases(expression)			TNF		D004137
CTD	increases(expression)			TNFAIP3		D004137
CTD	increases(expression)			TNFAIP6		D004137
CTD	decreases(reaction)			TXN		D004137
CTD	increases(expression)			TXN		D004137
CTD	affects(response to substance)			TXN		D004137
CTD	increases(expression)			TXN2		D004137
CTD	increases(expression)			TXNRD1		D004137
CTD	increases(expression)			TXNRD2		D004137
CTD	increases(expression)			UGT1A6		D004137
CTD	increases(expression)			VDR		D004137
CTD	decreases(expression)			ZBTB17		D004137
CTD	decreases(expression)			ZFP36L1		D004137
CTD	decreases(expression)			ZFYVE26		D004137
CTD	decreases(expression)			ZMYM3		D004137
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.635	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.767	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.924	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	19.496	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	19.496	AR	-	GI(Protien) :
PubChem	Potency	uM	17.783	ATXN2	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.206	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.635	CYP19A1	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	Potency	uM	5.173	IDH1	-	GI(Protien) :
PubChem	Potency	uM	14.125	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	Potency	uM	35.481	NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.709	PPARG	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.845	PPARG	-	GI(Protien) :
PubChem	Potency	uM	5.012	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	1.122	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.413	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.663	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.611	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.875	VDR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	22.218	VDR	-	GI(Protien) :

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