Tan Lab | DSigDB

Gene Set: D4 : CTD - Succimer

Collection

D4 : CTD

Chemical Name

Succimer ( From PubChem : SUCCIMER )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Not	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
182.218 g/mol	4	6	-0.2476	True

Structure

InChI

InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2-/m1/s1

InChIKey

ACTRVOBWPAIOHC-JCYAYHJZSA-N

Links

Gene (14 / 18)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(transport)			ABCC2		D004113
CTD	increases(activity)			TRPC5		D004113
PubChem	None	uM		BCL2L1	-	GI(Protien) :
PubChem	None	uM		CTDSP1	-	GI(Protien) :
PubChem	None	uM		CTDSP1	-	GI(Protien) :
PubChem	None	uM		DNMT1	-	GI(Protien) :
PubChem	IC50_Mean	uM	3.220	DUSP3	-	GI(Protien) :
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	None	uM		MCL1	-	GI(Protien) :
PubChem	Potency	uM	8.437	PLK1	-	GI(Protien) :
PubChem	IC50_Mean	uM	0.518	PTPN11	-	GI(Protien) :
PubChem	IC50	uM	4.480	PTPN22	-	GI(Protien) :
PubChem	IC50_Mean	uM	19.000	PTPN5	-	GI(Protien) :
PubChem	None	uM		PTPN5	-	GI(Protien) :
PubChem	None	uM		PTPN5	-	GI(Protien) :
PubChem	None	uM		SENP8	-	GI(Protien) :
ChEMBL	Potency	nM	50118.700	KDM4A	-	Target : CHEMBL5896

Download gene sets

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Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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