Tan Lab | DSigDB

Gene Set: D4 : CTD - Dilazep

Collection

D4 : CTD

Chemical Name

Dilazep ( From PubChem : DILAZEP )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
604.688 g/mol	0	12	3.4157	False(2/4)

Structure

InChI

InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3

InChIKey

QVZCXCJXTMIDME-UHFFFAOYSA-N

Links

Gene (6 / 14)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			SLC29A1		D004109
CTD	increases(uptake)			SLC29A1		D004109
PubChem	Potency	uM	10.000	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	11.004	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.882	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	16.789	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	16353.500	ATAD5	-	Target : CHEMBL1741209
ChEMBL	AC50	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	AC50	nM	7943.280	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	10000.000	THPO	-	Target : CHEMBL1293256

Download gene sets

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