Tan Lab | DSigDB

Gene Set: D4 : CTD - Diflunisal

Collection

D4 : CTD

Chemical Name

Diflunisal ( From PubChem : DIFLUNISAL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
250.198 g/mol	2	3	3.0356	True

Structure

InChI

InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)

InChIKey

Links

Gene (12 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			FOS		D004061
CTD	affects(binding)			TTR		D004061
CTD	decreases(response to substance)			TTR		D004061
CTD	decreases(activity)			UGT1A1		D004061
CTD	increases(glucuronidation)			UGT1A10		D004061
CTD	increases(glucuronidation)			UGT1A3		D004061
CTD	increases(glucuronidation)			UGT1A7		D004061
CTD	increases(glucuronidation)			UGT1A8		D004061
CTD	decreases(reaction)			UGT2B7		D004061
CTD	increases(chemical synthesis)			UGT2B7		D004061
CTD	increases(glucuronidation)			UGT2B7		D004061
CTD	increases(glucuronidation)			UGT2B7		D004061
CTD	increases(glucuronidation)			UGT2B7		D004061
PubChem	Potency-Replicate_1	uM	13.332	NFE2L2	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
PubChem	None	uM		SLC12A5	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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