Tan Lab | DSigDB

Gene Set: D4 : CTD - Dieldrin

Collection

D4 : CTD

Chemical Name

Dieldrin ( From PubChem : DIELDRIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
380.909 g/mol	0	1	4.4814	True

Structure

InChI

InChI=1S/C12H8Cl6O/c13-8-9(14)11(16)5-3-1-2(6-7(3)19-6)4(5)10(8,15)12(11,17)18/h2-7H,1H2

InChIKey

DFBKLUNHFCTMDC-UHFFFAOYSA-N

Links

Gene (45 / 123)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		D004026
CTD	increases(expression)			ABCC2		D004026
CTD	increases(expression)			ABCG2		D004026
CTD	affects(cotreatment)			ACVR1C		D004026
CTD	increases(expression)			ACVR1C		D004026
CTD	affects(cotreatment)			ACVRL1		D004026
CTD	increases(expression)			ACVRL1		D004026
CTD	increases(activity)			AHR		D004026
CTD	affects(cotreatment)			ALK		D004026
CTD	increases(expression)			ALK		D004026
CTD	decreases(reaction)			AR		D004026
CTD	increases(expression)			AR		D004026
CTD	decreases(reaction)			AR		D004026
CTD	increases(activity)			AR		D004026
CTD	decreases(reaction)			AR		D004026
CTD	increases(activity)			AR		D004026
CTD	decreases(reaction)			BCL2		D004026
CTD	increases(activity)			BCL2		D004026
CTD	decreases(reaction)			BCL2		D004026
CTD	increases(activity)			BCL2		D004026
CTD	decreases(response to substance)			BCL2		D004026
CTD	decreases(reaction)			CASP3		D004026
CTD	increases(activity)			CASP3		D004026
CTD	decreases(reaction)			CYP26A1		D004026
CTD	increases(expression)			CYP26A1		D004026
CTD	decreases(reaction)			CYP26A1		D004732
CTD	increases(expression)			CYP26A1		D004732
CTD	increases(expression)			CYP2B6		D004026
CTD	increases(expression)			CYP2B6		D004732
CTD	increases(expression)			CYP3A4		D004026
CTD	increases(reaction)			CYP3A4		D004026
CTD	increases(expression)			CYP3A4		D004026
CTD	increases(expression)			CYP3A4		D004732
CTD	affects(cotreatment)			ERBB3		D004026
CTD	increases(expression)			ERBB3		D004026
CTD	affects(cotreatment)			ESR1		D004026
CTD	increases(expression)			ESR1		D004026
CTD	affects(binding)			ESR1		D004026
CTD	increases(activity)			ESR1		D004026
CTD	affects(binding)			ESR1		D004026
CTD	affects(binding)			ESR1		D004026
CTD	affects(cotreatment)			ESR1		D004026
CTD	decreases(reaction)			ESR1		D004026
CTD	decreases(reaction)			ESR1		D004026
CTD	decreases(expression)			ESR1		D004026
CTD	decreases(reaction)			ESR1		D004026
CTD	increases(activity)			ESR1		D004026
CTD	increases(expression)			ESR1		D004026
CTD	affects(cotreatment)			ESR1		D004026
CTD	increases(expression)			ESR1		D004026
CTD	affects(binding)			ESR1		D004732
CTD	increases(activity)			ESR1		D004732
CTD	increases(activity)			ESR1		D004732
CTD	affects(binding)			ESR2		D004026
CTD	decreases(activity)			ESR2		D004026
CTD	increases(expression)			ESR2		D004026
CTD	increases(reaction)			ESR2		D004026
CTD	affects(binding)			ESR2		D004732
CTD	decreases(activity)			ESR2		D004732
CTD	affects(binding)			GABRA1		D004026
CTD	decreases(reaction)			GABRA1		D004026
CTD	affects(binding)			GABRA2		D004026
CTD	decreases(reaction)			GABRA2		D004026
CTD	affects(binding)			GABRB2		D004026
CTD	decreases(reaction)			GABRB2		D004026
CTD	affects(binding)			GABRG2		D004026
CTD	decreases(reaction)			GABRG2		D004026
CTD	affects(binding)			GABRR1		D004026
CTD	affects(cotreatment)			GJA1		D004026
CTD	decreases(expression)			GJA1		D004026
CTD	increases(phosphorylation)			JUN		D004026
CTD	affects(cotreatment)			KIT		D004026
CTD	increases(expression)			KIT		D004026
CTD	increases(activity)			MAP2K1		D004026
CTD	increases(phosphorylation)			MAP2K1		D004026
CTD	increases(activity)			MAP2K2		D004026
CTD	increases(phosphorylation)			MAP2K2		D004026
CTD	decreases(reaction)			MAPK1		D004026
CTD	increases(phosphorylation)			MAPK1		D004026
CTD	increases(activity)			MAPK1		D004026
CTD	decreases(reaction)			MAPK3		D004026
CTD	increases(phosphorylation)			MAPK3		D004026
CTD	increases(activity)			MAPK3		D004026
CTD	affects(binding)			NR1I2		D004026
CTD	increases(activity)			NR1I2		D004026
CTD	increases(expression)			NR1I2		D004026
CTD	increases(reaction)			NR1I2		D004026
CTD	increases(activity)			NR1I2		D004026
CTD	affects(binding)			NR1I2		D004732
CTD	increases(activity)			NR1I2		D004732
CTD	increases(activity)			NR1I2		D004732
CTD	affects(cotreatment)			PDGFRA		D004026
CTD	increases(expression)			PDGFRA		D004026
CTD	affects(cotreatment)			PDGFRB		D004026
CTD	increases(expression)			PDGFRB		D004026
CTD	decreases(reaction)			PRKCD		D004026
CTD	increases(activity)			PRKCD		D004026
CTD	increases(activity)			RAF1		D004026
CTD	increases(phosphorylation)			RAF1		D004026
CTD	increases(expression)			RARB		D004026
CTD	increases(expression)			RARB		D004732
CTD	increases(expression)			RARG		D004026
CTD	increases(expression)			RARG		D004732
CTD	decreases(expression)			SLC10A1		D004026
CTD	decreases(activity)			SLC22A1		D004026
CTD	decreases(reaction)			VEGFA		D004026
CTD	increases(secretion)			VEGFA		D004026
PubChem	Potency	uM	35.481	KCNH2		GI(Protien) :
PubChem	Potency	uM	35.481	KCNH2		GI(Protien) :
PubChem	Potency	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	12.589	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	25.119	TSHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	38.900	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	17.229	CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	54.483	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.811	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.872	NR3C1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.942	HSPB1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	TSHR	-	Target : CHEMBL1963

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