Tan Lab | DSigDB

Gene Set: D4 : CTD - Diazoxide

Collection

D4 : CTD

Chemical Name

Diazoxide ( From PubChem : DIAZOXIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
230.671 g/mol	1	4	2.527	True

Structure

InChI

InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)

InChIKey

Links

Gene (14 / 29)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			BCL2L1		D003981
CTD	increases(expression)			BCL2L1		D003981
CTD	decreases(reaction)			CCND1		D003981
CTD	increases(activity)			CCND1		D003981
CTD	decreases(expression)			CCND1		D003981
CTD	decreases(reaction)			CTNNB1		D003981
CTD	increases(activity)			CTNNB1		D003981
CTD	decreases(expression)			CTNNB1		D003981
CTD	decreases(reaction)			GCG		D003981
CTD	increases(secretion)			GCG		D003981
CTD	decreases(secretion)			IL10		D003981
CTD	decreases(secretion)			IL6		D003981
CTD	decreases(expression)			KCNJ11		D003981
CTD	decreases(reaction)			NAMPT		D003981
CTD	increases(secretion)			NAMPT		D003981
CTD	decreases(reaction)			NFKB1		D003981
CTD	increases(activity)			NFKB1		D003981
CTD	decreases(secretion)			TNF		D003981
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	2.818	EHMT2	-	GI(Protien) :
ChEMBL	AC50	nM	3162.280	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	1995.260	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	7943.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	7943.280	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	2818.400	EHMT2	-	Target : CHEMBL6032

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