Tan Lab | DSigDB

Gene Set: D4 : CTD - Diamide

Collection

D4 : CTD

Chemical Name

Diamide ( From PubChem : DIAMIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
172.185 g/mol	0	6	0.8018	True

Structure

InChI

InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+

InChIKey

VLSDXINSOMDCBK-BQYQJAHWSA-N

Links

Gene (19 / 39)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ATP7A		D003958
CTD	increases(reaction)			ATP7A		D003958
CTD	affects(binding)			ATP7B		D003958
CTD	increases(reaction)			ATP7B		D003958
CTD	affects(cotreatment)			CFTR		D003958
CTD	decreases(activity)			CFTR		D003958
CTD	affects(binding)			CLU		D003958
CTD	increases(reaction)			CLU		D003958
CTD	increases(expression)			HMOX1		D003958
CTD	affects(binding)			MTOR		D003958
CTD	decreases(reaction)			MTOR		D003958
CTD	increases(activity)			MTOR		D003958
CTD	increases(phosphorylation)			MTOR		D003958
CTD	decreases(activity)			OGG1		D003958
CTD	increases(oxidation)			OGG1		D003958
CTD	decreases(response to substance)			RFK		D003958
CTD	increases(activity)			RPS6KB1		D003958
CTD	increases(phosphorylation)			RPS6KB1		D003958
CTD	decreases(reaction)			RPS6KB1		D003958
CTD	affects(binding)			RPTOR		D003958
CTD	decreases(reaction)			RPTOR		D003958
CTD	increases(phosphorylation)			RPTOR		D003958
CTD	increases(expression)			SOD2		D003958
CTD	affects(localization)			STAT3		D003958
CTD	increases(glutathionylation)			TP53		D003958
PubChem	Potency	uM	19.953	CBX1	-	GI(Protien) :
PubChem	Potency	uM	2.668	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	7.943	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	7.943	MAPT	-	GI(Protien) :
PubChem	Potency	uM	14.125	MAPT	-	GI(Protien) :
PubChem	Potency	uM	31.623	MPHOSPH8	-	GI(Protien) :
PubChem	Potency	uM	2.994	RGS4	-	GI(Protien) :
PubChem	Potency	uM	6.310	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	19952.600	CBX1	-	Target : CHEMBL1741193
ChEMBL	Potency	nM	2667.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	7943.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	14125.400	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	7943.300	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	31622.800	MPHOSPH8	-	Target : CHEMBL1741210

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