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Gene Set: D4 : CTD - Dextromethorphan

Collection D4 : CTD
Chemical Name Dextromethorphan ( From PubChem : DEXTROMETHORPHAN )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotApprovedNotApprovedNot2
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
271.397 g/mol 0 2 3.3213 True
Structure
InChI InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
InChIKey MKXZASYAUGDDCJ-NJAFHUGGSA-N
Links

Gene (11 / 38)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(metabolic processing)CYP1A2
D003915
CTDaffects(metabolic processing)CYP2C19
D003915
CTDincreases(response to substance)CYP2D6
D003915
CTDaffects(metabolic processing)CYP2D6
D003915
CTDaffects(metabolic processing)CYP2D6
D003915
CTDaffects(metabolic processing)CYP2D6
D003915
CTDdecreases(methylation)CYP2D6
D003915
CTDincreases(metabolic processing)CYP2D6
D003915
CTDdecreases(methylation)CYP2D6
D003915
CTDdecreases(reaction)CYP2D6
D003915
CTDaffects(metabolic processing)CYP2D6
D003915
CTDdecreases(reaction)CYP2D6
D003915
CTDdecreases(reaction)CYP2D6
D003915
CTDincreases(metabolic processing)CYP2D6
D003915
CTDdecreases(reaction)CYP2D6
D003915
CTDincreases(metabolic processing)CYP2D6
D003915
CTDaffects(metabolic processing)CYP3A
D003915
CTDincreases(metabolic processing)CYP3A
D003915
CTDaffects(metabolic processing)CYP3A4
D003915
CTDdecreases(methylation)CYP3A4
D003915
CTDincreases(metabolic processing)CYP3A4
D003915
CTDincreases(oxidation)CYP3A4
D003915
CTDaffects(cotreatment)CYP3A4
D003915
CTDdecreases(activity)CYP3A4
D003915
CTDdecreases(reaction)CYP3A4
D003915
CTDaffects(metabolic processing)CYP3A5
D003915
CTDdecreases(methylation)CYP3A5
D003915
CTDincreases(oxidation)CYP3A5
D003915
CTDdecreases(methylation)CYP46A1
D003915
CTDdecreases(activity)KCNH2
D003915
CTDaffects(metabolic processing)NAT2
D003915
CTDdecreases(reaction)SLC22A2
D003915
CTDincreases(uptake)SLC22A2
D003915
CTDaffects(metabolic processing)XDH
D003915
PubChem PotencyuM2.512CYP2D6-GI(Protien) :
PubChem NoneuMCYP2D6-GI(Protien) :
ChEMBLPotencynM2511.900CYP2D6
-Target : CHEMBL289
ChEMBLAC50nM2511.890CYP2D6
-Target : CHEMBL289
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