Tan Lab | DSigDB

Gene Set: D4 : CTD - Desoxycorticosterone

Collection

D4 : CTD

Chemical Name

Desoxycorticosterone ( From PubChem : DESOXYCORTONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
330.461 g/mol	1	3	3.6959	True

Structure

InChI

InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1

InChIKey

ZESRJSPZRDMNHY-YFWFAHHUSA-N

Links

Gene (9 / 26)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			AR		D003900
CTD	increases(activity)			AR		D003900
CTD	affects(metabolic processing)			CYP11B1		D003900
CTD	increases(chemical synthesis)			CYP11B1		D003900
CTD	affects(metabolic processing)			CYP11B2		D003900
CTD	increases(hydroxylation)			CYP11B2		D003900
CTD	increases(chemical synthesis)			CYP11B2		D003900
CTD	affects(binding)			NR3C1		D003900
CTD	increases(activity)			NR3C1		D003900
CTD	increases(phosphorylation)			NR3C1		D003900
CTD	increases(abundance)			POMC		D003900
CTD	increases(expression)			PPARGC1A		D003900
PubChem	Potency-Replicate_1	uM	0.087	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.088	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.090	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.102	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.522	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	8.635	AR	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.696	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.811	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.977	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	5.701	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.322	TDP1	-	GI(Protien) :

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