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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Dichlorodiphenyldichloroethane

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Collection	D4 : CTD
Chemical Name	Dichlorodiphenyldichloroethane ( From PubChem : P,P'-DDD )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 320.041 g/mol 0 0 5.929 False(3/4)
Structure
InChI	InChI=1S/C14H10Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13-14H
InChIKey	AHJKRLASYNVKDZ-UHFFFAOYSA-N
Links
Gene (19 / 40) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(cotreatment) ACVR1C D003632 CTD increases(expression) ACVR1C D003632 CTD affects(cotreatment) ACVRL1 D003632 CTD increases(expression) ACVRL1 D003632 CTD affects(cotreatment) ALK D003632 CTD increases(expression) ALK D003632 CTD affects(binding) AR D003632 CTD decreases(reaction) AR D003632 CTD increases(expression) AR D003632 CTD decreases(reaction) AR D003632 CTD increases(activity) AR D003632 CTD increases(activity) CREBBP D003632 CTD increases(expression) CYP2B6 D003632 CTD increases(expression) CYP3A4 D003632 CTD affects(cotreatment) ERBB3 D003632 CTD increases(expression) ERBB3 D003632 CTD increases(activity) ESR1 D003632 CTD increases(expression) ESR1 D003632 CTD increases(activity) ESR2 D003632 CTD affects(cotreatment) KIT D003632 CTD increases(expression) KIT D003632 CTD affects(binding) NR1I2 D003632 CTD increases(activity) NR1I2 D003632 CTD affects(cotreatment) PDGFRA D003632 CTD increases(expression) PDGFRA D003632 CTD affects(cotreatment) PDGFRB D003632 CTD increases(expression) PDGFRB D003632 CTD increases(expression) PTGS2 D003632 PubChem Ratio Potency (uM) uM 38.895 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 44.363 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 48.966 AR - GI(Protien) : PubChem AR Potency (uM) uM 72.434 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 62.127 CYP19A1 - GI(Protien) : PubChem Potency uM 39.811 ESR1 - GI(Protien) : PubChem Potency uM 22.387 KCNH2 GI(Protien) : PubChem Potency uM 22.387 KCNH2 GI(Protien) : PubChem Potency uM 61.131 NFE2L2 - GI(Protien) : PubChem Potency uM 66.824 NFE2L2 - GI(Protien) : PubChem Potency-Replicate_1 uM 39.811 NR1I2 - GI(Protien) : PubChem Potency-Replicate_1 uM 24.947 NR3C1 - GI(Protien) :
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