Tan Lab | DSigDB

Gene Set: D4 : CTD - Cytochalasin B

Collection

D4 : CTD

Chemical Name

Cytochalasin B ( From PubChem : CYTOCHALASIN B )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
479.608 g/mol	3	6	3.8209	True

Structure

InChI

InChI=1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,31,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)

InChIKey

GBOGMAARMMDZGR-UHFFFAOYSA-N

Links

Gene (32 / 66)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			C5		D003571
CTD	increases(activity)			C5		D003571
CTD	increases(phosphorylation)			C5		D003571
CTD	increases(secretion)			C5		D003571
CTD	decreases(reaction)			C5		D003571
CTD	decreases(reaction)			CAT		D003571
CTD	increases(expression)			CAT		D003571
CTD	decreases(reaction)			CSF2		D003571
CTD	increases(secretion)			CSF2		D003571
CTD	affects(cotreatment)			ELANE		D003571
CTD	increases(secretion)			ELANE		D003571
CTD	decreases(reaction)			ELANE		D003571
CTD	affects(cotreatment)			EPO		D003571
CTD	increases(secretion)			EPO		D003571
CTD	decreases(reaction)			EPO		D003571
CTD	affects(cotreatment)			IL1B		D003571
CTD	decreases(reaction)			IL1B		D003571
CTD	increases(secretion)			IL1B		D003571
CTD	affects(cotreatment)			IL5		D003571
CTD	increases(secretion)			IL5		D003571
CTD	decreases(reaction)			IL5		D003571
CTD	affects(cotreatment)			MAPK1		D003571
CTD	increases(activity)			MAPK1		D003571
CTD	increases(phosphorylation)			MAPK1		D003571
CTD	decreases(reaction)			MAPK1		D003571
CTD	affects(cotreatment)			MAPK3		D003571
CTD	increases(activity)			MAPK3		D003571
CTD	increases(phosphorylation)			MAPK3		D003571
CTD	decreases(reaction)			MAPK3		D003571
CTD	affects(folding)			SLC2A1		D003571
CTD	decreases(reaction)			SLC2A1		D003571
CTD	increases(transport)			SLC2A1		D003571
CTD	decreases(reaction)			SLC2A2		D003571
CTD	increases(transport)			SLC2A2		D003571
CTD	decreases(reaction)			SLC2A3		D003571
CTD	increases(transport)			SLC2A3		D003571
CTD	decreases(reaction)			SOD2		D003571
CTD	increases(expression)			SOD2		D003571
PubChem	None	uM		APP	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	5.805	GMNN	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	Potency	uM	1.300	IDH1	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		NCF1	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		S1PR1	-	GI(Protien) :
PubChem	None	uM		S1PR4	-	GI(Protien) :
PubChem	None	uM		S1PR4	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	Potency	uM	0.609	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.651	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.683	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.836	TDP1	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :

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