Tan Lab | DSigDB

Gene Set: D4 : CTD - Coumaphos

Collection

D4 : CTD

Chemical Name

Coumaphos ( From PubChem : COUMAPHOS )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
362.766 g/mol	0	6	5.0817	False(3/4)

Structure

InChI

InChI=1S/C14H16ClO5PS/c1-4-17-21(22,18-5-2)20-10-6-7-11-9(3)13(15)14(16)19-12(11)8-10/h6-8H,4-5H2,1-3H3

InChIKey

Links

Gene (8 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			RARA		D003372
PubChem	AhR Potency (uM)	uM	0.043	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	0.065	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.098	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	0.438	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.596	AHR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	39.338	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.338	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	46.227	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.131	AR	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.536	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.778	NR1I2	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	Potency	uM	6.513	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	1995.300	CYP3A4	-	Target : CHEMBL340

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