Tan Lab | DSigDB

Gene Set: D4 : CTD - Codeine

Collection

D4 : CTD

Chemical Name

Codeine ( From PubChem : ISOCODEINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
299.364 g/mol	1	4	1.439	True

Structure

InChI

InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13+,17-,18-/m0/s1

InChIKey

Links

Gene (9 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(secretion)			CCL2		D003061
CTD	affects(expression)			CCL5		D003061
CTD	affects(secretion)			CCL5		D003061
CTD	affects(expression)			CXCL8		D003061
CTD	affects(secretion)			CXCL8		D003061
CTD	increases(activity)			CYP2D6		D003061
CTD	increases(response to substance)			CYP2D6		D003061
CTD	increases(metabolic processing)			CYP2D6		D003061
CTD	affects(metabolic processing)			CYP2D6		D003061
CTD	affects(metabolic processing)			CYP2D6		D003061
CTD	affects(response to substance)			CYP2D6		D003061
CTD	decreases(methylation)			CYP2D6		D003061
CTD	increases(metabolic processing)			CYP2D6		D003061
CTD	increases(chemical synthesis)			CYP2D6		D003061
CTD	increases(metabolic processing)			CYP2D6		D003061
CTD	affects(metabolic processing)			CYP3A4		D003061
CTD	decreases(activity)			KCNH2		D003061
PubChem	Potency-Replicate_1	uM	61.441	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	28.519	NFE2L2	-	GI(Protien) :
ChEMBL	Activity	-		ABCB1	-	Target : CHEMBL4302

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