Tan Lab | DSigDB

Gene Set: D4 : CTD - Cocaine

Collection

D4 : CTD

Chemical Name

Cocaine ( From PubChem : ALLOCOCAINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
303.353 g/mol	0	5	1.8056	True

Structure

InChI

InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15-/m0/s1

InChIKey

ZPUCINDJVBIVPJ-XGUBFFRZSA-N

Links

Gene (290 / 415)

⊖ Less

Source	Type	Gene	Other
CTD	affects(abundance)	ACE	D003042
CTD	decreases(reaction)	ACE	D003042
CTD	decreases(expression)	ACTG2	D003042
CTD	increases(expression)	ACTN2	D003042
CTD	decreases(expression)	AIF1L	D003042
CTD	increases(expression)	AIFM1	D003042
CTD	decreases(expression)	AK1	D003042
CTD	decreases(expression)	AP2S1	D003042
CTD	increases(expression)	APCS	D003042
CTD	increases(expression)	APOL2	D003042
CTD	increases(expression)	APP	D003042
CTD	decreases(expression)	ARHGAP29	D003042
CTD	affects(expression)	ATP5A1	D003042
CTD	decreases(expression)	ATP5B	D003042
CTD	decreases(expression)	ATP5G3	D003042
CTD	affects(response to substance)	ATP9B	D003042
CTD	decreases(expression)	ATXN3	D003042
CTD	increases(expression)	BAX	D003042
CTD	affects(hydrolysis)	BCHE	D003042
CTD	affects(metabolic processing)	BCHE	D003042
CTD	increases(hydrolysis)	BCHE	D003042
CTD	affects(degradation)	BCHE	D003042
CTD	decreases(metabolic processing)	BCHE	D003042
CTD	decreases(response to substance)	BCHE	D003042
CTD	increases(hydrolysis)	BCHE	D003042
CTD	increases(metabolic processing)	BCHE	D003042
CTD	increases(metabolic processing)	BCHE	D003042
CTD	decreases(response to substance)	BDNF	D003042
CTD	decreases(expression)	CALM1	D003042
CTD	decreases(expression)	CALM2	D003042
CTD	decreases(expression)	CAMK2B	D003042
CTD	increases(response to substance)	CAMK4	D003042
CTD	decreases(expression)	CAPZB	D003042
CTD	increases(expression)	CARTPT	D003042
CTD	increases(expression)	CASP3	D003042
CTD	decreases(expression)	CASP4	D003042
CTD	increases(expression)	CASP9	D003042
CTD	decreases(expression)	CCKBR	D003042
CTD	increases(secretion)	CCL2	D003042
CTD	increases(secretion)	CCL3	D003042
CTD	decreases(expression)	CCNA2	D003042
CTD	increases(expression)	CCR5	D003042
CTD	affects(response to substance)	CCSER1	D003042
CTD	decreases(expression)	CCZ1	D003042
CTD	decreases(expression)	CD44	D003042
CTD	increases(response to substance)	CD81	D003042
CTD	decreases(expression)	CDH1	D003042
CTD	decreases(expression)	CDH17	D003042
CTD	increases(hydrolysis)	CES1	D003042
CTD	affects(cotreatment)	CES1	D003042
CTD	increases(metabolic processing)	CES1	D003042
CTD	affects(binding)	CES1	D003042
CTD	decreases(reaction)	CES1	D003042
CTD	increases(chemical synthesis)	CES1	D003042
CTD	decreases(reaction)	CES1	D003042
CTD	increases(hydrolysis)	CES1	D003042
CTD	increases(hydrolysis)	CES1	D003042
CTD	increases(hydrolysis)	CES2	D003042
CTD	decreases(reaction)	CES2	D003042
CTD	increases(chemical synthesis)	CES2	D003042
CTD	increases(hydrolysis)	CES2	D003042
CTD	decreases(expression)	CES2	D003042
CTD	decreases(response to substance)	CHRNA5	D003042
CTD	decreases(expression)	CHURC1	D003042
CTD	affects(binding)	CKB	D003042
CTD	increases(secretion)	CKB	D003042
CTD	affects(binding)	CKM	D003042
CTD	increases(secretion)	CKM	D003042
CTD	decreases(expression)	CLDN11	D003042
CTD	decreases(expression)	CLIC1	D003042
CTD	increases(expression)	CLIP1	D003042
CTD	decreases(expression)	CLTB	D003042
CTD	increases(expression)	CNKSR2	D003042
CTD	affects(response to substance)	CNR1	D003042
CTD	affects(response to substance)	CNR1	D003042
CTD	affects(response to substance)	CNR1	D003042
CTD	affects(response to substance)	COL21A1	D003042
CTD	decreases(expression)	COX6C	D003042
CTD	increases(expression)	CRP	D003042
CTD	decreases(expression)	CRYAB	D003042
CTD	decreases(expression)	CRYBB2	D003042
CTD	decreases(expression)	CSRP2	D003042
CTD	decreases(expression)	CTGF	D003042
CTD	decreases(expression)	CTNNBIP1	D003042
CTD	decreases(expression)	CTNND2	D003042
CTD	increases(expression)	CUL4B	D003042
CTD	increases(secretion)	CXCL10	D003042
CTD	increases(secretion)	CXCL8	D003042
CTD	increases(expression)	CXCR4	D003042
CTD	decreases(expression)	CYC1	D003042
CTD	decreases(expression)	CYP2C8	D003042
CTD	decreases(expression)	CYP2C9	D003042
CTD	decreases(expression)	CYP51A1	D003042
CTD	increases(response to substance)	DBH	D003042
CTD	decreases(expression)	DDX41	D003042
CTD	decreases(expression)	DEAF1	D003042
CTD	affects(response to substance)	DNAH8	D003042
CTD	decreases(expression)	DNPH1	D003042
CTD	increases(expression)	DPF2	D003042
CTD	affects(binding)	DRD1	D003042
CTD	decreases(reaction)	DRD1	D003042
CTD	increases(activity)	DRD1	D003042
CTD	increases(phosphorylation)	DRD1	D003042
CTD	increases(reaction)	DRD1	D003042
CTD	affects(localization)	DRD1	D003042
CTD	affects(folding)	DRD1	D003042
CTD	affects(binding)	DRD2	D003042
CTD	affects(reaction)	DRD2	D003042
CTD	decreases(expression)	DRD2	D003042
CTD	decreases(expression)	DRD2	D003042
CTD	increases(response to substance)	DRD2	D003042
CTD	decreases(expression)	DRD3	D003042
CTD	affects(response to substance)	DRD3	D003042
CTD	increases(response to substance)	DRD4	D003042
CTD	affects(expression)	DRP2	D003042
CTD	increases(expression)	DSP	D003042
CTD	decreases(expression)	DYNC1I1	D003042
CTD	increases(expression)	EDN1	D003042
CTD	increases(expression)	EDNRA	D003042
CTD	decreases(expression)	EEF1G	D003042
CTD	decreases(expression)	EGFR	D003042
CTD	decreases(expression)	EIF5A	D003042
CTD	increases(expression)	EIF5A	D003042
CTD	affects(binding)	ELANE	D003042
CTD	affects(reaction)	ELANE	D003042
CTD	decreases(activity)	ELANE	D003042
CTD	decreases(expression)	ENHO	D003042
CTD	decreases(expression)	ENO2	D003042
CTD	increases(expression)	ENO2	D003042
CTD	increases(expression)	ENPP5	D003042
CTD	decreases(expression)	EPHB4	D003042
CTD	increases(expression)	EYA1	D003042
CTD	decreases(expression)	EZR	D003042
CTD	affects(expression)	FAHD2A	D003042
CTD	increases(expression)	FAM153A	D003042
CTD	increases(expression)	FAS	D003042
CTD	increases(expression)	FDFT1	D003042
CTD	decreases(expression)	FGF2	D003042
CTD	affects(expression)	FLNB	D003042
CTD	increases(expression)	FLRT3	D003042
CTD	affects(cotreatment)	FOS	D003042
CTD	increases(expression)	FOS	D003042
CTD	decreases(reaction)	FOS	D003042
CTD	increases(expression)	FOS	D003042
CTD	increases(expression)	FOSB	D003042
CTD	decreases(expression)	FOSL1	D003042
CTD	affects(binding)	FOSL2	D003042
CTD	increases(reaction)	FOSL2	D003042
CTD	decreases(expression)	FOSL2	D003042
CTD	affects(binding)	GABRA1	D003042
CTD	decreases(activity)	GABRA1	D003042
CTD	increases(reaction)	GABRA1	D003042
CTD	affects(binding)	GABRB2	D003042
CTD	decreases(activity)	GABRB2	D003042
CTD	increases(reaction)	GABRB2	D003042
CTD	affects(binding)	GABRG2	D003042
CTD	decreases(activity)	GABRG2	D003042
CTD	increases(reaction)	GABRG2	D003042
CTD	decreases(expression)	GAD1	D003042
CTD	decreases(expression)	GAP43	D003042
CTD	increases(expression)	GCC1	D003042
CTD	increases(expression)	GEM	D003042
CTD	increases(expression)	GFAP	D003042
CTD	decreases(reaction)	GH1	D003042
CTD	increases(secretion)	GH1	D003042
CTD	decreases(reaction)	GH1	D003042
CTD	increases(expression)	GH1	D003042
CTD	decreases(expression)	GJB2	D003042
CTD	decreases(expression)	GNAO1	D003042
CTD	decreases(expression)	GNB1	D003042
CTD	decreases(expression)	GPM6A	D003042
CTD	decreases(expression)	GPM6B	D003042
CTD	increases(expression)	GRIA2	D003042
CTD	increases(expression)	GRIA3	D003042
CTD	increases(expression)	GRIN1	D003042
CTD	decreases(expression)	GSN	D003042
CTD	affects(expression)	GSTO1	D003042
CTD	affects(response to substance)	GSTP1	D003042
CTD	increases(expression)	HCN2	D003042
CTD	decreases(expression)	HIF1A	D003042
CTD	increases(response to substance)	HOMER1	D003042
CTD	decreases(expression)	HPCAL1	D003042
CTD	increases(expression)	HSPA5	D003042
CTD	affects(expression)	HSPD1	D003042
CTD	affects(response to substance)	ICE2	D003042
CTD	affects(secretion)	IFNG	D003042
CTD	affects(cotreatment)	IFNG	D003042
CTD	increases(expression)	IFNG	D003042
CTD	decreases(expression)	IFNG	D003042
CTD	affects(cotreatment)	IL10	D003042
CTD	increases(expression)	IL10	D003042
CTD	decreases(secretion)	IL10	D003042
CTD	increases(expression)	IL10	D003042
CTD	increases(expression)	IL1B	D003042
CTD	affects(cotreatment)	IL2	D003042
CTD	increases(expression)	IL2	D003042
CTD	affects(cotreatment)	IL4	D003042
CTD	increases(expression)	IL4	D003042
CTD	decreases(expression)	IL6	D003042
CTD	decreases(expression)	INHA	D003042
CTD	decreases(expression)	INS	D003042
CTD	decreases(expression)	IRF9	D003042
CTD	increases(expression)	ITGB1BP1	D003042
CTD	increases(expression)	ITGB6	D003042
CTD	affects(binding)	JUN	D003042
CTD	increases(reaction)	JUN	D003042
CTD	increases(expression)	JUN	D003042
CTD	affects(expression)	JUNB	D003042
CTD	decreases(expression)	JUND	D003042
CTD	decreases(expression)	KCNJ6	D003042
CTD	increases(expression)	KL	D003042
CTD	affects(response to substance)	KLHL5	D003042
CTD	increases(expression)	KRIT1	D003042
CTD	increases(expression)	LAMB1	D003042
CTD	decreases(expression)	LDB2	D003042
CTD	increases(expression)	LEMD3	D003042
CTD	increases(expression)	LIN7C	D003042
CTD	decreases(expression)	LPAR1	D003042
CTD	affects(response to substance)	LRRC7	D003042
CTD	increases(expression)	MAL2	D003042
CTD	affects(response to substance)	MANEA	D003042
CTD	decreases(expression)	MAP1B	D003042
CTD	decreases(expression)	MAP2K1	D003042
CTD	affects(binding)	MAPK1	D003042
CTD	decreases(reaction)	MAPK1	D003042
CTD	increases(activity)	MAPK1	D003042
CTD	increases(phosphorylation)	MAPK1	D003042
CTD	increases(reaction)	MAPK1	D003042
CTD	decreases(expression)	MAPK10	D003042
CTD	affects(binding)	MAPK3	D003042
CTD	decreases(reaction)	MAPK3	D003042
CTD	increases(activity)	MAPK3	D003042
CTD	increases(phosphorylation)	MAPK3	D003042
CTD	increases(reaction)	MAPK3	D003042
CTD	increases(expression)	MAPK3	D003042
CTD	increases(expression)	MARCH7	D003042
CTD	decreases(expression)	MBP	D003042
CTD	decreases(expression)	MDH1	D003042
CTD	decreases(reaction)	MECP2	D003042
CTD	increases(expression)	MECP2	D003042
CTD	decreases(expression)	MEF2D	D003042
CTD	decreases(reaction)	MIR132	D003042
CTD	increases(expression)	MIR132	D003042
CTD	decreases(reaction)	MIR212	D003042
CTD	increases(expression)	MIR212	D003042
CTD	decreases(activity)	MMP9	D003042
CTD	decreases(expression)	MMP9	D003042
CTD	decreases(expression)	NDRG2	D003042
CTD	affects(expression)	NDUFA10	D003042
CTD	affects(expression)	NDUFS2	D003042
CTD	increases(expression)	NEDD4L	D003042
CTD	decreases(expression)	NEFL	D003042
CTD	decreases(expression)	NEFM	D003042
CTD	increases(expression)	NETO2	D003042
CTD	increases(expression)	NFE2L1	D003042
CTD	increases(expression)	NFYB	D003042
CTD	decreases(expression)	NGF	D003042
CTD	affects(expression)	NME2	D003042
CTD	decreases(expression)	NOS3	D003042
CTD	increases(expression)	NPIPB3	D003042
CTD	increases(expression)	NPPA	D003042
CTD	decreases(expression)	NR1I3	D003042
CTD	decreases(expression)	NR3C1	D003042
CTD	decreases(expression)	NR4A2	D003042
CTD	decreases(expression)	NSF	D003042
CTD	decreases(expression)	NTRK2	D003042
CTD	decreases(expression)	NUCKS1	D003042
CTD	increases(expression)	OPHN1	D003042
CTD	decreases(expression)	OPRM1	D003042
CTD	affects(binding)	OPRM1	D003042
CTD	affects(reaction)	OPRM1	D003042
CTD	increases(response to substance)	OPRM1	D003042
CTD	decreases(expression)	OSBPL1A	D003042
CTD	decreases(expression)	PAK6	D003042
CTD	increases(expression)	PAX8	D003042
CTD	increases(expression)	PCDH8	D003042
CTD	increases(expression)	PCDHA2	D003042
CTD	increases(expression)	PCDHGA1	D003042
CTD	decreases(expression)	PCSK1N	D003042
CTD	decreases(expression)	PCSK2	D003042
CTD	increases(expression)	PDCD7	D003042
CTD	decreases(expression)	PDE4DIP	D003042
CTD	increases(expression)	PDYN	D003042
CTD	increases(expression)	PDYN	D003042
CTD	affects(response to substance)	PDYN	D003042
CTD	decreases(response to substance)	PDYN	D003042
CTD	increases(response to substance)	PDYN	D003042
CTD	affects(expression)	PEBP1	D003042
CTD	decreases(expression)	PENK	D003042
CTD	increases(expression)	PF4	D003042
CTD	increases(expression)	PFN1	D003042
CTD	decreases(expression)	PIM1	D003042
CTD	decreases(expression)	PITX3	D003042
CTD	affects(expression)	PLP1	D003042
CTD	decreases(expression)	PLP1	D003042
CTD	increases(expression)	PMEPA1	D003042
CTD	increases(secretion)	POMC	D003042
CTD	decreases(expression)	PPAP2C	D003042
CTD	increases(expression)	PPBP	D003042
CTD	increases(expression)	PPFIA3	D003042
CTD	increases(expression)	PPFIBP1	D003042
CTD	increases(expression)	PPID	D003042
CTD	decreases(expression)	PPP1CA	D003042
CTD	decreases(expression)	PPP2CA	D003042
CTD	decreases(expression)	PPP2CB	D003042
CTD	decreases(expression)	PPP2R2C	D003042
CTD	affects(expression)	PRDX2	D003042
CTD	decreases(expression)	PRDX2	D003042
CTD	affects(expression)	PRDX5	D003042
CTD	increases(expression)	PREPL	D003042
CTD	decreases(expression)	PRKCB	D003042
CTD	affects(expression)	PRL	D003042
CTD	affects(reaction)	PRL	D003042
CTD	increases(expression)	PRL	D003042
CTD	affects(secretion)	PRL	D003042
CTD	decreases(reaction)	PRL	D003042
CTD	increases(expression)	PRL	D003042
CTD	decreases(expression)	PRL	D003042
CTD	decreases(secretion)	PRL	D003042
CTD	increases(expression)	PRL	D003042
CTD	affects(binding)	PRTN3	D003042
CTD	affects(reaction)	PRTN3	D003042
CTD	increases(expression)	PSME4	D003042
CTD	decreases(expression)	PTK2	D003042
CTD	decreases(expression)	PTN	D003042
CTD	decreases(expression)	PTPRA	D003042
CTD	decreases(expression)	PTPRB	D003042
CTD	decreases(expression)	PVALB	D003042
CTD	increases(expression)	RECK	D003042
CTD	decreases(expression)	RPS10	D003042
CTD	decreases(expression)	RPS9	D003042
CTD	decreases(expression)	RPSA	D003042
CTD	increases(expression)	RYBP	D003042
CTD	increases(expression)	SCARB1	D003042
CTD	affects(localization)	SELP	D003042
CTD	increases(expression)	SEMA3B	D003042
CTD	decreases(expression)	SEMA6A	D003042
CTD	decreases(expression)	SEPT4	D003042
CTD	decreases(expression)	SGCB	D003042
CTD	increases(expression)	SGCB	D003042
CTD	increases(expression)	SGK3	D003042
CTD	decreases(expression)	SHANK2	D003042
CTD	affects(binding)	SIGMAR1	D003042
CTD	decreases(reaction)	SIGMAR1	D003042
CTD	increases(activity)	SIGMAR1	D003042
CTD	increases(phosphorylation)	SIGMAR1	D003042
CTD	increases(reaction)	SIGMAR1	D003042
CTD	affects(localization)	SIGMAR1	D003042
CTD	affects(folding)	SIGMAR1	D003042
CTD	increases(expression)	SLC10A1	D003042
CTD	decreases(expression)	SLC18A2	D003042
CTD	decreases(expression)	SLC22A14	D003042
CTD	decreases(expression)	SLC25A23	D003042
CTD	increases(expression)	SLC25A37	D003042
CTD	increases(expression)	SLC35A3	D003042
CTD	decreases(activity)	SLC6A2	D003042
CTD	increases(expression)	SLC6A2	D003042
CTD	decreases(reaction)	SLC6A3	D003042
CTD	increases(uptake)	SLC6A3	D003042
CTD	affects(binding)	SLC6A3	D003042
CTD	affects(cotreatment)	SLC6A3	D003042
CTD	increases(expression)	SLC6A3	D003042
CTD	decreases(reaction)	SLC6A3	D003042
CTD	decreases(reaction)	SLC6A3	D003042
CTD	increases(localization)	SLC6A3	D003042
CTD	decreases(reaction)	SLC6A3	D003042
CTD	increases(transport)	SLC6A3	D003042
CTD	affects(binding)	SLC6A3	D003042
CTD	increases(reaction)	SLC6A3	D003042
CTD	decreases(expression)	SLC6A3	D003042
CTD	increases(expression)	SLC6A3	D003042
CTD	increases(response to substance)	SLC6A3	D003042
CTD	affects(binding)	SLC6A4	D003042
CTD	decreases(activity)	SLC6A4	D003042
CTD	decreases(activity)	SLC6A4	D003042
CTD	increases(expression)	SLC6A4	D003042
CTD	decreases(expression)	SLC9A2	D003042
CTD	affects(expression)	SNCA	D003042
CTD	increases(expression)	SNCA	D003042
CTD	increases(expression)	SNCA	D003042
CTD	decreases(expression)	SOD1	D003042
CTD	decreases(expression)	SPG7	D003042
CTD	decreases(expression)	SPTBN1	D003042
CTD	decreases(expression)	SSR4	D003042
CTD	increases(expression)	ST3GAL6	D003042
CTD	increases(expression)	SYT11	D003042
CTD	affects(response to substance)	SYT13	D003042
CTD	increases(response to substance)	TACR3	D003042
CTD	decreases(expression)	TAGLN3	D003042
CTD	affects(response to substance)	TENM3	D003042
CTD	decreases(expression)	TF	D003042
CTD	increases(expression)	TFAP4	D003042
CTD	increases(expression)	TFRC	D003042
CTD	increases(expression)	TIPRL	D003042
CTD	affects(expression)	TKT	D003042
CTD	affects(cotreatment)	TNF	D003042
CTD	increases(expression)	TNF	D003042
CTD	decreases(expression)	TNF	D003042
CTD	increases(secretion)	TNF	D003042
CTD	increases(expression)	TNFRSF14	D003042
CTD	increases(secretion)	TNNI3	D003042
CTD	decreases(expression)	TOB1	D003042
CTD	decreases(expression)	TP53INP2	D003042
CTD	decreases(expression)	TUBA3C	D003042
CTD	decreases(expression)	TUBA3D	D003042
CTD	decreases(expression)	TUBA4A	D003042
CTD	decreases(expression)	TUBA8	D003042
CTD	affects(response to substance)	TYK2	D003042
CTD	increases(expression)	UBE2I	D003042
CTD	decreases(expression)	UBE2M	D003042
CTD	decreases(expression)	UCHL1	D003042
CTD	increases(expression)	UGCG	D003042
CTD	increases(expression)	VWF	D003042
CTD	increases(expression)	YWHAE	D003042
CTD	decreases(expression)	YWHAH	D003042

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