Tan Lab | DSigDB

Gene Set: D4 : CTD - Clorgyline

Collection

D4 : CTD

Chemical Name

Clorgyline ( From PubChem : CLORGILINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
272.17 g/mol	0	2	3.3273	True

Structure

InChI

InChI=1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3

InChIKey

BTFHLQRNAMSNLC-UHFFFAOYSA-N

Links

Gene (167 / 184)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCA5		D003010
CTD	increases(expression)			ACADSB		D003010
CTD	increases(expression)			ACAP2		D003010
CTD	increases(expression)			ADRB2		D003010
CTD	increases(expression)			AKAP11		D003010
CTD	increases(expression)			AKAP9		D003010
CTD	increases(expression)			ANKRD12		D003010
CTD	increases(expression)			APC		D003010
CTD	increases(expression)			AR		D003010
CTD	increases(expression)			ARAP2		D003010
CTD	increases(expression)			ARID4A		D003010
CTD	increases(expression)			ATG4C		D003010
CTD	increases(expression)			ATRX		D003010
CTD	increases(expression)			AZI2		D003010
CTD	increases(expression)			B3GNT5		D003010
CTD	increases(expression)			BAZ2B		D003010
CTD	increases(expression)			BDP1		D003010
CTD	increases(expression)			BOD1L1		D003010
CTD	increases(expression)			BRWD1		D003010
CTD	increases(expression)			CACNB2		D003010
CTD	increases(expression)			CBLN2		D003010
CTD	increases(expression)			CCDC112		D003010
CTD	increases(expression)			CDH23		D003010
CTD	increases(expression)			CENPC		D003010
CTD	increases(expression)			CEP135		D003010
CTD	increases(expression)			CEP290		D003010
CTD	increases(expression)			CEP350		D003010
CTD	increases(expression)			CEP70		D003010
CTD	increases(expression)			CFH		D003010
CTD	increases(expression)			CHD9		D003010
CTD	increases(expression)			CHIC1		D003010
CTD	increases(expression)			CHM		D003010
CTD	increases(expression)			CLGN		D003010
CTD	increases(expression)			CLIP1		D003010
CTD	increases(expression)			CNTN3		D003010
CTD	increases(expression)			COBLL1		D003010
CTD	increases(expression)			CPD		D003010
CTD	increases(expression)			CPNE9		D003010
CTD	increases(expression)			CTAGE5		D003010
CTD	increases(expression)			DKKL1		D003010
CTD	increases(expression)			DMXL1		D003010
CTD	increases(expression)			DNAJC10		D003010
CTD	increases(expression)			DST		D003010
CTD	increases(expression)			DYNC2H1		D003010
CTD	increases(expression)			DYNC2LI1		D003010
CTD	increases(expression)			ECHDC1		D003010
CTD	increases(expression)			ESCO1		D003010
CTD	decreases(expression)			EZH2		D003010
CTD	increases(expression)			FAS		D003010
CTD	increases(expression)			FZD3		D003010
CTD	increases(expression)			GABPA		D003010
CTD	increases(expression)			GCC2		D003010
CTD	increases(expression)			GK		D003010
CTD	increases(expression)			GNPDA2		D003010
CTD	increases(expression)			GOLGA4		D003010
CTD	increases(expression)			GOLGB1		D003010
CTD	increases(expression)			HBBP1		D003010
CTD	increases(expression)			HBD		D003010
CTD	increases(expression)			HINT3		D003010
CTD	increases(expression)			IBTK		D003010
CTD	increases(expression)			IFT80		D003010
CTD	increases(expression)			KLHDC1		D003010
CTD	increases(expression)			KLHL2		D003010
CTD	increases(expression)			KLK3		D003010
CTD	increases(expression)			KTN1		D003010
CTD	increases(expression)			LARP1B		D003010
CTD	increases(expression)			LIG4		D003010
CTD	increases(expression)			LRAT		D003010
CTD	increases(expression)			LTB		D003010
CTD	increases(expression)			MAGEA3		D003010
CTD	increases(expression)			MANEA		D003010
CTD	decreases(activity)			MAOA		D003010
CTD	increases(expression)			MAP9		D003010
CTD	increases(expression)			MBNL2		D003010
CTD	increases(expression)			MIPOL1		D003010
CTD	increases(expression)			MOB1B		D003010
CTD	increases(expression)			MON2		D003010
CTD	increases(expression)			MOSPD2		D003010
CTD	increases(expression)			MPP7		D003010
CTD	increases(expression)			MYO6		D003010
CTD	increases(expression)			NDFIP2		D003010
CTD	increases(expression)			NFE2L2		D003010
CTD	increases(expression)			NIPBL		D003010
CTD	increases(expression)			NPAT		D003010
CTD	increases(expression)			NRIP1		D003010
CTD	increases(expression)			NSRP1		D003010
CTD	increases(expression)			NSUN3		D003010
CTD	increases(expression)			NT5DC1		D003010
CTD	increases(expression)			NUDCD1		D003010
CTD	increases(expression)			ODF2L		D003010
CTD	increases(expression)			PCM1		D003010
CTD	increases(expression)			PCMTD1		D003010
CTD	increases(expression)			PDIK1L		D003010
CTD	increases(expression)			PHF14		D003010
CTD	increases(expression)			PHF3		D003010
CTD	increases(expression)			PHIP		D003010
CTD	increases(expression)			PIK3C2A		D003010
CTD	increases(expression)			POLK		D003010
CTD	increases(expression)			PREX2		D003010
CTD	increases(expression)			PRODH2		D003010
CTD	increases(expression)			PTPN22		D003010
CTD	increases(expression)			RAD50		D003010
CTD	increases(expression)			RAD54B		D003010
CTD	increases(expression)			RAPGEF4		D003010
CTD	increases(expression)			RB1CC1		D003010
CTD	increases(expression)			REV3L		D003010
CTD	increases(expression)			RGPD5		D003010
CTD	increases(expression)			RGS5		D003010
CTD	increases(expression)			RICTOR		D003010
CTD	increases(expression)			SAMD9		D003010
CTD	increases(expression)			SCAF11		D003010
CTD	increases(expression)			SEMA3C		D003010
CTD	increases(expression)			SENP6		D003010
CTD	increases(expression)			SENP7		D003010
CTD	increases(expression)			SEPP1		D003010
CTD	increases(expression)			SHOC2		D003010
CTD	increases(expression)			SLC4A5		D003010
CTD	increases(expression)			SLCO1B1		D003010
CTD	increases(expression)			SLITRK6		D003010
CTD	increases(expression)			SLK		D003010
CTD	increases(expression)			SMCHD1		D003010
CTD	increases(expression)			SNORD64		D003010
CTD	increases(expression)			SOCS2		D003010
CTD	increases(expression)			STAG2		D003010
CTD	increases(expression)			STEAP2		D003010
CTD	increases(expression)			STXBP4		D003010
CTD	increases(expression)			TAS2R45		D003010
CTD	increases(expression)			TBC1D15		D003010
CTD	increases(expression)			TBC1D8B		D003010
CTD	increases(expression)			TCEAL7		D003010
CTD	increases(expression)			TEX9		D003010
CTD	increases(expression)			THAP2		D003010
CTD	increases(expression)			TMED5		D003010
CTD	increases(expression)			TMEM106B		D003010
CTD	increases(expression)			TMF1		D003010
CTD	increases(expression)			TRIP11		D003010
CTD	increases(expression)			UBE2W		D003010
CTD	increases(expression)			UBLCP1		D003010
CTD	increases(expression)			UPF3B		D003010
CTD	increases(expression)			UTRN		D003010
CTD	increases(expression)			VCPIP1		D003010
CTD	increases(expression)			VPS13A		D003010
CTD	increases(expression)			VPS13C		D003010
CTD	increases(expression)			VPS37A		D003010
CTD	increases(expression)			WDR17		D003010
CTD	increases(expression)			ZBTB1		D003010
CTD	increases(expression)			ZBTB10		D003010
CTD	increases(expression)			ZCCHC6		D003010
CTD	increases(expression)			ZFY		D003010
CTD	increases(expression)			ZFYVE16		D003010
CTD	increases(expression)			ZNF138		D003010
CTD	increases(expression)			ZNF141		D003010
CTD	increases(expression)			ZNF280C		D003010
CTD	increases(expression)			ZNF280D		D003010
CTD	increases(expression)			ZNF292		D003010
CTD	increases(expression)			ZNF449		D003010
CTD	increases(expression)			ZNF480		D003010
CTD	increases(expression)			ZNF493		D003010
CTD	increases(expression)			ZNF567		D003010
CTD	increases(expression)			ZNF638		D003010
CTD	increases(expression)			ZNF644		D003010
CTD	increases(expression)			ZNF658B		D003010
CTD	increases(expression)			ZNF721		D003010
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	0.398	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	1.995	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	10.000	TSHR	-	GI(Protien) :
ChEMBL	AC50	nM	158.490	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	630.960	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	2511.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	2511.890	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	5011.870	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	5011.900	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	1995.260	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	398.110	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	398.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	1995.300	CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		MAOA	-	Target : CHEMBL1951
ChEMBL	Potency	nM	10000.000	TSHR	-	Target : CHEMBL1963

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