Tan Lab | DSigDB

Gene Set: D4 : CTD - Clofibric Acid

Collection

D4 : CTD

Chemical Name

Clofibric Acid ( From PubChem : CLOFIBRIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
214.646 g/mol	1	3	2.582	True

Structure

InChI

InChI=1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChIKey

Links

Gene (20 / 29)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ANGPTL4		D002995
CTD	increases(expression)			CPT1A		D002995
CTD	decreases(expression)			CXCL12		D002995
CTD	decreases(activity)			CYP2A6		D002995
CTD	decreases(expression)			CYP2A6		D002995
CTD	increases(activity)			CYP2C8		D002995
CTD	increases(expression)			CYP2C8		D002995
CTD	increases(expression)			CYP2C9		D002995
CTD	increases(activity)			CYP3A4		D002995
CTD	increases(expression)			CYP3A4		D002995
CTD	increases(expression)			PLIN2		D002995
CTD	affects(binding)			PPARA		D002995
CTD	affects(binding)			PPARD		D002995
CTD	affects(binding)			PPARG		D002995
CTD	decreases(expression)			RBP1		D002995
CTD	increases(expression)			SERPINE1		D002995
CTD	increases(secretion)			SERPINE1		D002995
CTD	increases(expression)			UGT1A1		D002995
CTD	increases(glucuronidation)			UGT1A10		D002995
CTD	increases(glucuronidation)			UGT1A3		D002995
CTD	increases(glucuronidation)			UGT1A7		D002995
CTD	increases(glucuronidation)			UGT1A8		D002995
CTD	increases(glucuronidation)			UGT2B7		D002995
CTD	increases(glucuronidation)			UGT2B7		D002995
PubChem	Potency	uM	5.012	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		PPARG	-	GI(Protien) :
ChEMBL	AC50	nM	5011.870	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	5011.900	CYP2D6	-	Target : CHEMBL289

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