Tan Lab | DSigDB

Gene Set: D4 : CTD - Clobetasol

Collection

D4 : CTD

Chemical Name

Clobetasol ( From PubChem : CLOBETASOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
410.907 g/mol	2	4	3.1422	True

Structure

InChI

InChI=1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

FCSHDIVRCWTZOX-DVTGEIKXSA-N

Links

Gene (8 / 14)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCC1		D002990
CTD	increases(expression)			CYP1A1		D002990
CTD	decreases(reaction)			CYP1A1		D002990
CTD	increases(expression)			CYP3A5		D002990
CTD	decreases(expression)			GCLC		D002990
PubChem	Potency-Replicate_1	uM	6.682	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	13.333	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.790	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	8.817	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	10.682	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.001	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.002	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.053	TDP1	-	GI(Protien) :

Download gene sets

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