Tan Lab | DSigDB

Gene Set: D4 : CTD - Cinnarizine

Collection

D4 : CTD

Chemical Name

Cinnarizine ( From PubChem : CINNARIZINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
368.514 g/mol	0	2	4.9828	True

Structure

InChI

InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+

InChIKey

Links

Gene (14 / 17)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ABCB11		D002936
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	None	uM		ESR2	-	GI(Protien) :
PubChem	Potency	uM	1.000	KCNH2		GI(Protien) :
PubChem	Potency	uM	1.000	KCNH2		GI(Protien) :
PubChem	None	uM		MAP4K2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.332	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	12.589	NPSR1	-	GI(Protien) :
ChEMBL	Activity	-		CDK1	-	Target : CHEMBL308
ChEMBL	Activity	-		CDK1	-	Target : CHEMBL308
ChEMBL	Activity	-		CFL1	-	Target : CHEMBL1075129
ChEMBL	Activity	-		JUN	-	Target : CHEMBL4977
ChEMBL	Potency	nM	12589.300	NPSR1	-	Target : CHEMBL5162
ChEMBL	Activity	-		TP53	-	Target : CHEMBL4096

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