Tan Lab | DSigDB

Gene Set: D4 : CTD - Chlorzoxazone

Collection

D4 : CTD

Chemical Name

Chlorzoxazone ( From PubChem : CHLORZOXAZONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
169.565 g/mol	1	2	1.7745	True

Structure

InChI

InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10)

InChIKey

Links

Gene (8 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(hydroxylation)			CYB5A		D002753
CTD	increases(reaction)			CYB5A		D002753
CTD	affects(metabolic processing)			CYP1A2		D002753
CTD	decreases(reaction)			CYP2E1		D002753
CTD	increases(hydroxylation)			CYP2E1		D002753
CTD	decreases(activity)			CYP2E1		D002753
CTD	decreases(degradation)			CYP2E1		D002753
CTD	increases(hydroxylation)			CYP2E1		D002753
CTD	increases(reaction)			CYP2E1		D002753
CTD	affects(hydroxylation)			CYP2E1		D002753
CTD	affects(metabolic processing)			CYP2E1		D002753
CTD	increases(hydroxylation)			CYP2E1		D002753
CTD	increases(metabolic processing)			CYP2E1		D002753
CTD	increases(chemical synthesis)			CYP2E1		D002753
CTD	increases(metabolic processing)			CYP2E1		D002753
CTD	increases(oxidation)			CYP2E1		D002753
CTD	decreases(reaction)			CYP2E1		D002753
CTD	decreases(reaction)			CYP2E1		D002753
CTD	increases(oxidation)			CYP2E1		D002753
CTD	increases(activity)			KCNN4		D002753
CTD	affects(metabolic processing)			NAT2		D002753
CTD	affects(metabolic processing)			XDH		D002753
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
ChEMBL	AC50	nM	5011.870	CYP1A2	-	Target : CHEMBL3356
ChEMBL	AC50	nM	398.110	CYP1A2	-	Target : CHEMBL3356

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