Tan Lab | DSigDB

Gene Set: D4 : CTD - Chloramphenicol

Collection

D4 : CTD

Chemical Name

Chloramphenicol ( From PubChem : CHLORAMPHENICOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
323.129 g/mol	3	4	1.8231	True

Structure

InChI

InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

InChIKey

WIIZWVCIJKGZOK-RKDXNWHRSA-N

Links

Gene (22 / 41)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ALPL		D002701
CTD	increases(expression)			ATG12		D002701
CTD	decreases(reaction)			CASP3		D002701
CTD	increases(activity)			CASP3		D002701
CTD	increases(expression)			CAT		D002701
CTD	decreases(reaction)			CDKN1A		D002701
CTD	increases(activity)			CDKN1A		D002701
CTD	decreases(degradation)			CDKN1A		D002701
CTD	affects(localization)			CDKN1A		D002701
CTD	increases(expression)			CDKN1A		D002701
CTD	increases(expression)			CDKN2A		D002701
CTD	increases(expression)			COL1A1		D002701
CTD	decreases(expression)			COX1		D002701
CTD	decreases(reaction)			CYP3A4		D002701
CTD	increases(oxidation)			CYP3A4		D002701
CTD	increases(expression)			ESR1		D002701
CTD	decreases(reaction)			JUN		D002701
CTD	increases(phosphorylation)			JUN		D002701
CTD	affects(localization)			JUN		D002701
CTD	decreases(expression)			MMP10		D002701
CTD	decreases(reaction)			MMP13		D002701
CTD	increases(expression)			MMP13		D002701
CTD	increases(secretion)			MMP13		D002701
CTD	increases(expression)			MMP3		D002701
CTD	decreases(expression)			ND1		D002701
CTD	decreases(reaction)			PARP1		D002701
CTD	increases(activity)			PARP1		D002701
CTD	increases(expression)			POLG		D002701
CTD	increases(expression)			RRM2B		D002701
CTD	decreases(reaction)			SLC22A7		D002701
CTD	increases(transport)			SLC22A7		D002701
CTD	increases(expression)			TFAM		D002701
PubChem	Potency	uM	14.125	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	5.805	TDP1	-	GI(Protien) :
PubChem	Potency	uM	6.513	TDP1	-	GI(Protien) :
PubChem	Potency	uM	7.499	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.593	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.197	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	ALDH1A1	-	Target : CHEMBL3577

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