Tan Lab | DSigDB

Gene Set: D4 : CTD - Chalcone

Collection

D4 : CTD

Chemical Name

Chalcone ( From PubChem : CHALCONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
208.255 g/mol	0	1	3.5827	True

Structure

InChI

InChI=1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+

InChIKey

Links

Gene (13 / 32)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(cleavage)			CASP3		D002599
CTD	affects(response to substance)			CASP3		D002599
CTD	increases(cleavage)			CASP8		D002599
CTD	affects(response to substance)			CASP8		D002599
CTD	increases(cleavage)			CASP9		D002599
CTD	affects(response to substance)			CASP9		D002599
CTD	increases(abundance)			MYC		D002599
CTD	increases(reaction)			MYC		D002599
CTD	affects(response to substance)			MYC		D002599
CTD	increases(cleavage)			MYC		D002599
CTD	increases(cleavage)			PARP1		D002599
CTD	affects(response to substance)			PARP1		D002599
PubChem	IC50	uM	4.194	ABHD5	-	GI(Protien) :
PubChem	IC50	uM	4.245	ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		HNF4A	-	GI(Protien) :
PubChem	Potency	uM	16.360	IDH1	-	GI(Protien) :
PubChem	IC50	uM	4.194	PLIN1	-	GI(Protien) :
PubChem	None	uM		PLIN1	-	GI(Protien) :
PubChem	IC50	uM	4.245	PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	Potency	uM	22.387	POLI	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.220	VDR	-	GI(Protien) :
PubChem	Potency	uM	15.849	VDR	-	GI(Protien) :
PubChem	Potency	uM	17.783	VDR	-	GI(Protien) :
PubChem	Potency	uM	25.929	VDR	-	GI(Protien) :

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