Tan Lab | DSigDB

Gene Set: D4 : CTD - Carbonyl Cyanide m-Chlorophenyl Hydrazone

Collection

D4 : CTD

Chemical Name

Carbonyl Cyanide m-Chlorophenyl Hydrazone ( From PubChem : CCCP )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
204.616 g/mol	1	4	2.22806	True

Structure

InChI

InChI=1S/C9H5ClN4/c10-7-2-1-3-8(4-7)13-14-9(5-11)6-12/h1-4,13H

InChIKey

Links

Gene (13 / 22)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			CIRBP		D002258
CTD	decreases(reaction)			LEP		D002258
CTD	increases(chemical synthesis)			LEP		D002258
CTD	decreases(response to substance)			LEP		D002258
CTD	affects(localization)			PARK2		D002258
CTD	decreases(expression)			RBM3		D002258
PubChem	Potency-Replicate_1	uM	1.933	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.731	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	1.259	CYP3A4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.692	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.096	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	1.478	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.169	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.949	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	4.467	MAPT	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	Potency	uM	0.631	TSHR	-	GI(Protien) :
ChEMBL	Potency	nM	1258.900	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	4466.800	MAPT	-	Target : CHEMBL1293224
ChEMBL	Potency	nM	631.000	TSHR	-	Target : CHEMBL1963

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