Tan Lab | DSigDB

Gene Set: D4 : CTD - Carbachol

Collection

D4 : CTD

Chemical Name

Carbachol ( From PubChem : CARBACHOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
182.648 g/mol	1	3	-2.5078	True

Structure

InChI

InChI=1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

InChIKey

AIXAANGOTKPUOY-UHFFFAOYSA-N

Links

Gene (26 / 80)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	increases(hydrolysis)		ACHE		D002217
CTD	decreases(reaction)		ACHE		D002217
CTD	increases(metabolic processing)		ACHE		D002217
CTD	increases(secretion)		ACHE		D002217
CTD	affects(binding)		ACHE		D002217
CTD	affects(localization)		AQP5		D002217
CTD	decreases(reaction)		CD40		D002217
CTD	increases(expression)		CD40		D002217
CTD	affects(binding)		CHRM1		D002217
CTD	increases(reaction)		CHRM1		D002217
CTD	increases(activity)		CHRM1		D002217
CTD	increases(abundance)		CHRM1		D002217
CTD	increases(activity)		CHRM1		D002217
CTD	increases(activity)		CHRM1		D002217
CTD	increases(expression)		CHRM1		D002217
CTD	affects(binding)		CHRM2		D002217
CTD	increases(reaction)		CHRM2		D002217
CTD	decreases(reaction)		CHRM3		D002217
CTD	increases(activity)		CHRM3		D002217
CTD	affects(binding)		CHRM3		D002217
CTD	increases(reaction)		CHRM3		D002217
CTD	increases(activity)		CHRM3		D002217
CTD	increases(reaction)		CHRM3		D002217
CTD	affects(binding)		CHRM3		D002217
CTD	affects(binding)		CHRM3		D002217
CTD	increases(reaction)		CHRM3		D002217
CTD	affects(binding)		CHRM4		D002217
CTD	increases(reaction)		CHRM4		D002217
CTD	affects(binding)		CHRNA4		D002217
CTD	decreases(activity)		CHRNA4		D002217
CTD	decreases(reaction)		CHRNA4		D002217
CTD	increases(activity)		CHRNA4		D002217
CTD	affects(binding)		CHRNA7		D002217
CTD	decreases(reaction)		CHRNA7		D002217
CTD	affects(binding)		CHRNA7		D002217
CTD	decreases(reaction)		CHRNA7		D002217
CTD	affects(binding)		CHRNB2		D002217
CTD	decreases(activity)		CHRNB2		D002217
CTD	decreases(reaction)		CHRNB2		D002217
CTD	increases(activity)		CHRNB2		D002217
CTD	increases(activity)		FASLG		D002217
CTD	increases(expression)		FASLG		D002217
CTD	affects(binding)		GRM4		D002217
CTD	decreases(reaction)		GRM4		D002217
CTD	increases(activity)		GRM4		D002217
CTD	increases(import)		GRM4		D002217
CTD	affects(binding)		KCNJ3		D002217
CTD	decreases(reaction)		KCNJ3		D002217
CTD	increases(activity)		KCNJ3		D002217
CTD	increases(import)		KCNJ3		D002217
CTD	affects(secretion)		LYZ		D002217
CTD	increases(activity)		MAPK1		D002217
CTD	increases(activity)		MAPK3		D002217
CTD	decreases(reaction)		PRKCZ		D002217
CTD	increases(activity)		PRKCZ		D002217
CTD	increases(phosphorylation)		PRKCZ		D002217
CTD	decreases(reaction)		RPS6KB1		D002217
CTD	increases(activity)		RPS6KB1		D002217
CTD	increases(phosphorylation)		RPS6KB1		D002217
CTD	decreases(reaction)		TNF		D002217
CTD	increases(abundance)		TNF		D002217
CTD	affects(reaction)		TRPC4		D002217
CTD	increases(transport)		TRPC4		D002217
CTD	increases(reaction)		TRPC5		D002217
CTD	increases(transport)		TRPC5		D002217
CTD	decreases(reaction)		TRPC5		D002217
PubChem	None	uM	CHRM1	-	GI(Protien) :
PubChem	None	uM	CHRM1	-	GI(Protien) :
PubChem	None	uM	CHRM4	-	GI(Protien) :
PubChem	None	uM	CHRM4	-	GI(Protien) :
PubChem	None	uM	CHRM5	-	GI(Protien) :
PubChem	None	uM	CHRM5	-	GI(Protien) :
PubChem	None	uM	MRGPRX1	-	GI(Protien) :
PubChem	None	uM	MRGPRX1	-	GI(Protien) :
PubChem	None	uM	MRGPRX1	-	GI(Protien) :
PubChem	None	uM	PLCG1	-	GI(Protien) :
PubChem	None	uM	TRHR	-	GI(Protien) :
ChEMBL	Activity	-	CHRM1	-	Target : CHEMBL216
ChEMBL	Activity	-	CHRM1	-	Target : CHEMBL216
ChEMBL	Activity	-	P2RY2	-	Target : CHEMBL4398

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