Tan Lab | DSigDB

Gene Set: D4 : CTD - Biotin

Collection

D4 : CTD

Chemical Name

Biotin ( From PubChem : BIOTIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
244.311 g/mol	3	6	1.4544	True

Structure

InChI

InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChIKey

Links

Gene (23 / 41)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			CXCL11		D001710
CTD	increases(activity)			CYP1B1		D001710
CTD	increases(expression)			CYP1B1		D001710
CTD	increases(expression)			CYP1B1		D001710
CTD	decreases(reaction)			CYP2E1		D001710
CTD	increases(degradation)			CYP2E1		D001710
CTD	affects(cotreatment)			HBA1		D001710
CTD	decreases(expression)			HBA1		D001710
CTD	increases(expression)			HERC4		D001710
CTD	decreases(expression)			HIRA		D001710
CTD	increases(expression)			IGHG1		D001710
CTD	decreases(expression)			LAMP1		D001710
CTD	increases(expression)			PPARGC1A		D001710
CTD	decreases(reaction)			SLC5A6		D001710
CTD	increases(transport)			SLC5A6		D001710
CTD	affects(expression)			SLC5A6		D001710
CTD	increases(transport)			SLC5A6		D001710
CTD	increases(uptake)			SLC5A6		D001710
CTD	affects(reaction)			SLC5A6		D001710
CTD	increases(reaction)			SLC5A6		D001710
CTD	increases(expression)			TMPRSS15		D001710
CTD	increases(expression)			TPR		D001710
PubChem	IC50	uM	0.004	ABL1	-	GI(Protien) :
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	None	uM		ABL1	-	GI(Protien) :
PubChem	None	uM		EZH2	-	GI(Protien) :
PubChem	EC50	uM	2.373	IDE	-	GI(Protien) :
PubChem	EC50	uM	2.526	IDE	-	GI(Protien) :
PubChem	None	uM		IDE	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MLLT3	-	GI(Protien) :
PubChem	None	uM		NCOR2		GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		PPARG		GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	None	uM		PSIP1	-	GI(Protien) :
PubChem	IC50	uM	0.004	RIN1	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	None	uM		RIN1	-	GI(Protien) :
PubChem	None	uM		WHSC1	-	GI(Protien) :

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