Tan Lab | DSigDB

Gene Set: D4 : CTD - Bilirubin

Collection

D4 : CTD

Chemical Name

Bilirubin ( From PubChem : 635-65-4 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
584.662 g/mol	6	8	5.1888	False(1/4)

Structure

InChI

InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChIKey

BPYKTIZUTYGOLE-IFADSCNNSA-N

Links

Gene (151 / 203)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(transport)			ABCC1		D001663
CTD	increases(reaction)			ABCC1		D001663
CTD	decreases(reaction)			ABCC1		D001663
CTD	decreases(phosphorylation)			AKT1		D001663
CTD	decreases(reaction)			AKT1		D001663
CTD	decreases(expression)			ALAD		D001663
CTD	decreases(expression)			ANXA1		D001663
CTD	increases(expression)			AREG		D001663
CTD	decreases(expression)			ARHGAP29		D001663
CTD	decreases(expression)			ASB13		D001663
CTD	increases(expression)			ATF3		D001663
CTD	decreases(expression)			ATP1A1		D001663
CTD	decreases(expression)			AXIN2		D001663
CTD	decreases(expression)			BLOC1S1		D001663
CTD	decreases(expression)			C1D		D001663
CTD	decreases(expression)			CAT		D001663
CTD	decreases(expression)			CCDC80		D001663
CTD	decreases(expression)			CCND1		D001663
CTD	increases(expression)			CCRN4L		D001663
CTD	decreases(expression)			CD302		D001663
CTD	increases(expression)			CHAC1		D001663
CTD	increases(expression)			CHKA		D001663
CTD	decreases(expression)			CLCC1		D001663
CTD	decreases(expression)			CLIP1		D001663
CTD	decreases(expression)			COL3A1		D001663
CTD	decreases(expression)			COX15		D001663
CTD	decreases(expression)			CPD		D001663
CTD	increases(expression)			CSF2		D001663
CTD	decreases(expression)			CTSH		D001663
CTD	increases(expression)			CXCL10		D001663
CTD	increases(expression)			CXCL11		D001663
CTD	increases(expression)			CXCL2		D001663
CTD	increases(expression)			CYP1A1		D001663
CTD	decreases(expression)			CYP2A6		D001663
CTD	decreases(reaction)			CYP2A6		D001663
CTD	decreases(activity)			CYP2A6		D001663
CTD	increases(activity)			CYP2A6		D001663
CTD	increases(expression)			CYP2A6		D001663
CTD	increases(stability)			CYP2A6		D001663
CTD	increases(oxidation)			CYP2A6		D001663
CTD	increases(chemical synthesis)			CYP2A6		D001663
CTD	increases(expression)			CYP2B6		D001663
CTD	decreases(reaction)			CYP2B6		D001663
CTD	increases(expression)			CYP2C9		D001663
CTD	decreases(reaction)			CYP2C9		D001663
CTD	increases(expression)			CYP3A4		D001663
CTD	decreases(reaction)			CYP3A4		D001663
CTD	increases(expression)			DDIT3		D001663
CTD	decreases(expression)			DEPTOR		D001663
CTD	decreases(expression)			DMKN		D001663
CTD	affects(expression)			DNAJB1		D001663
CTD	decreases(expression)			DNPEP		D001663
CTD	decreases(expression)			DPY19L1		D001663
CTD	increases(expression)			DUSP5		D001663
CTD	decreases(expression)			EGLN1		D001663
CTD	decreases(expression)			EI24		D001663
CTD	decreases(expression)			EID1		D001663
CTD	increases(activity)			EIF2AK3		D001663
CTD	increases(phosphorylation)			EIF2AK3		D001663
CTD	increases(activity)			EIF2S1		D001663
CTD	increases(phosphorylation)			EIF2S1		D001663
CTD	decreases(expression)			ENDOD1		D001663
CTD	decreases(expression)			FAM174A		D001663
CTD	increases(expression)			FOSL1		D001663
CTD	increases(expression)			GADD45B		D001663
CTD	decreases(expression)			GAS5		D001663
CTD	decreases(expression)			GSN		D001663
CTD	increases(expression)			GSTA1		D001663
CTD	decreases(reaction)			GSTA1		D001663
CTD	increases(expression)			GSTA2		D001663
CTD	decreases(reaction)			GSTA2		D001663
CTD	decreases(expression)			GSTA3		D001663
CTD	decreases(expression)			GSTA4		D001663
CTD	decreases(expression)			GSTK1		D001663
CTD	decreases(expression)			GSTM1		D001663
CTD	decreases(expression)			GSTP1		D001663
CTD	decreases(expression)			HACD4		D001663
CTD	decreases(expression)			HEPH		D001663
CTD	increases(expression)			HERPUD1		D001663
CTD	increases(expression)			HIST1H1E		D001663
CTD	increases(expression)			HIST1H2BC		D001663
CTD	increases(expression)			HIST1H4I		D001663
CTD	increases(expression)			HIST3H2A		D001663
CTD	affects(activity)			HMOX1		D001663
CTD	decreases(activity)			HMOX1		D001663
CTD	decreases(reaction)			HMOX1		D001663
CTD	increases(chemical synthesis)			HMOX1		D001663
CTD	increases(expression)			HMOX1		D001663
CTD	increases(abundance)			HMOX1		D001663
CTD	increases(expression)			HMOX1		D001663
CTD	increases(abundance)			HMOX1		D001663
CTD	increases(expression)			HSPA5		D001663
CTD	decreases(expression)			IDH2		D001663
CTD	increases(expression)			IFRD1		D001663
CTD	decreases(expression)			IGFBP3		D001663
CTD	decreases(phosphorylation)			IL18		D001663
CTD	decreases(reaction)			IL18		D001663
CTD	increases(expression)			IL18		D001663
CTD	decreases(response to substance)			IL18		D001663
CTD	decreases(reaction)			IL1B		D001663
CTD	increases(expression)			IL1B		D001663
CTD	increases(expression)			IL6		D001663
CTD	decreases(expression)			LAMB1		D001663
CTD	decreases(expression)			LAMP2		D001663
CTD	decreases(expression)			LEPROT		D001663
CTD	increases(expression)			LIF		D001663
CTD	decreases(expression)			LRP1		D001663
CTD	decreases(expression)			MAF		D001663
CTD	decreases(phosphorylation)			MAPK1		D001663
CTD	decreases(phosphorylation)			MAPK3		D001663
CTD	decreases(expression)			MAPRE2		D001663
CTD	decreases(expression)			ME2		D001663
CTD	decreases(expression)			MEGF9		D001663
CTD	decreases(expression)			MGST2		D001663
CTD	increases(expression)			MMP13		D001663
CTD	decreases(expression)			MPZL2		D001663
CTD	decreases(expression)			MRPL18		D001663
CTD	decreases(expression)			NID1		D001663
CTD	decreases(expression)			NNT		D001663
CTD	increases(expression)			NR1I2		D001663
CTD	increases(expression)			NR1I3		D001663
CTD	increases(expression)			OSGIN1		D001663
CTD	decreases(expression)			PDK1		D001663
CTD	decreases(expression)			PGAP2		D001663
CTD	decreases(expression)			PHB		D001663
CTD	decreases(expression)			PIAS1		D001663
CTD	decreases(expression)			PIK3R1		D001663
CTD	decreases(expression)			PLA1A		D001663
CTD	decreases(expression)			PMP22		D001663
CTD	decreases(expression)			PON2		D001663
CTD	decreases(expression)			PRDX4		D001663
CTD	decreases(reaction)			PTEN		D001663
CTD	increases(expression)			PTEN		D001663
CTD	increases(expression)			RASSF4		D001663
CTD	decreases(expression)			RBM39		D001663
CTD	decreases(expression)			RBM5		D001663
CTD	decreases(expression)			RHOBTB3		D001663
CTD	decreases(expression)			RNASE4		D001663
CTD	decreases(expression)			S100A10		D001663
CTD	decreases(expression)			S100A4		D001663
CTD	decreases(expression)			SCP2		D001663
CTD	decreases(expression)			SELENBP1		D001663
CTD	increases(expression)			SERPINE1		D001663
CTD	decreases(expression)			SESN1		D001663
CTD	decreases(expression)			SGPP1		D001663
CTD	decreases(expression)			SLC16A12		D001663
CTD	increases(expression)			SLC23A1		D001663
CTD	increases(expression)			SLC23A2		D001663
CTD	affects(cotreatment)			SLC3A2		D001663
CTD	increases(activity)			SLC3A2		D001663
CTD	increases(uptake)			SLC3A2		D001663
CTD	increases(abundance)			SLC3A2		D001663
CTD	decreases(response to substance)			SLC3A2		D001663
CTD	increases(expression)			SLC3A2		D001663
CTD	affects(cotreatment)			SLC7A11		D001663
CTD	increases(activity)			SLC7A11		D001663
CTD	increases(uptake)			SLC7A11		D001663
CTD	increases(abundance)			SLC7A11		D001663
CTD	decreases(response to substance)			SLC7A11		D001663
CTD	increases(expression)			SLC7A11		D001663
CTD	decreases(reaction)			SLCO1B1		D001663
CTD	increases(import)			SLCO1B1		D001663
CTD	increases(expression)			SLCO1B1		D001663
CTD	decreases(reaction)			SLCO1B1		D001663
CTD	decreases(expression)			SNX14		D001663
CTD	decreases(expression)			SOST		D001663
CTD	decreases(expression)			SP5		D001663
CTD	decreases(expression)			TAPBP		D001663
CTD	decreases(expression)			TCF4		D001663
CTD	increases(expression)			TIPARP		D001663
CTD	decreases(expression)			TM9SF2		D001663
CTD	decreases(expression)			TNFRSF19		D001663
CTD	decreases(expression)			TPP1		D001663
CTD	decreases(expression)			TRIB2		D001663
CTD	decreases(expression)			UBE2I		D001663
CTD	decreases(activity)			UGT1A1		D001663
CTD	increases(expression)			UGT1A1		D001663
CTD	affects(glucuronidation)			UGT1A1		D001663
CTD	increases(reaction)			UGT1A1		D001663
CTD	decreases(reaction)			UGT1A1		D001663
CTD	decreases(glucuronidation)			UGT1A1		D001663
CTD	decreases(activity)			UGT1A1		D001663
CTD	increases(glucuronidation)			UGT1A1		D001663
CTD	increases(glucuronidation)			UGT1A1		D001663
CTD	increases(metabolic processing)			UGT1A1		D001663
CTD	decreases(activity)			UGT1A3		D001663
CTD	decreases(activity)			UGT2B15		D001663
CTD	decreases(expression)			UQCR11		D001663
CTD	decreases(expression)			UQCRB		D001663
CTD	decreases(expression)			UQCRC1		D001663
CTD	decreases(expression)			UQCRH		D001663
CTD	decreases(expression)			UXS1		D001663
CTD	decreases(expression)			VLDLR		D001663
CTD	decreases(expression)			ZBTB20		D001663
CTD	decreases(expression)			ZBTB8OS		D001663
CTD	decreases(expression)			ZCCHC7		D001663
CTD	increases(expression)			ZFAND2A		D001663
PubChem	None	uM		BLVRA	-	GI(Protien) :
PubChem	None	uM		HSD11B1	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPT	-	GI(Protien) :
PubChem	None	uM		PECR	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	10000.000	MAPT	-	Target : CHEMBL1293224

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