Tan Lab | DSigDB

Gene Set: D4 : CTD - Betamethasone

Collection

D4 : CTD

Chemical Name

Betamethasone ( From PubChem : BETAMETHASONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
392.461 g/mol	3	5	1.8957	True

Structure

InChI

InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChIKey

UREBDLICKHMUKA-DVTGEIKXSA-N

Links

Gene (17 / 36)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			CCL2		D001623
CTD	increases(expression)			CCL3		D001623
CTD	increases(expression)			CCL4		D001623
CTD	decreases(reaction)			CXCL8		D001623
CTD	increases(expression)			CXCL8		D001623
CTD	affects(expression)			EGR1		D001623
CTD	increases(expression)			FXN		D001623
CTD	increases(activity)			HPGD		D001623
CTD	increases(expression)			HPGD		D001623
CTD	increases(metabolic processing)			HSD11B2		D001623
CTD	affects(binding)			NR3C1		D001623
CTD	increases(activity)			NR3C1		D001623
CTD	decreases(reaction)			NR3C1		D001623
CTD	increases(activity)			NR3C1		D001623
CTD	increases(activity)			NR3C2		D001623
CTD	decreases(expression)			VEGFA		D001623
PubChem	AhR Potency (uM)	uM	24.337	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.001	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.002	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.005	AR	-	GI(Protien) :
PubChem	Potency	uM	0.010	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.011	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.011	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.038	AR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	None	uM		GALR3	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	0.005	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.016	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.004	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.005	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.025	NR3C1	-	GI(Protien) :
PubChem	Potency	uM	0.089	NR3C1	-	GI(Protien) :
ChEMBL	Potency	nM	16.400	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

gmt, text, Detailed text