Tan Lab | DSigDB

Gene Set: D4 : CTD - Azinphosmethyl

Collection

D4 : CTD

Chemical Name

Azinphosmethyl ( From PubChem : AZINPHOS-METHYL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
317.324 g/mol	0	8	2.6501	True

Structure

InChI

InChI=1S/C10H12N3O3PS2/c1-15-17(18,16-2)19-7-13-10(14)8-5-3-4-6-9(8)11-12-13/h3-6H,7H2,1-2H3

InChIKey

CJJOSEISRRTUQB-UHFFFAOYSA-N

Links

Gene (21 / 36)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		D001387
CTD	decreases(reaction)			AR		D001387
CTD	increases(expression)			AR		D001387
PubChem	Potency	uM	7.943	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALOX15	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.483	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	31.623	ESR1	-	GI(Protien) :
PubChem	Potency	uM	10.000	HPGD	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	39.811	KAT2A	-	GI(Protien) :
PubChem	Potency	uM	31.623	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	22.387	MAPT	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	17.903	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	8.437	PLK1	-	GI(Protien) :
PubChem	None	uM		PPARD	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	PPARG	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	Potency	uM	23.109	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.912	VDR	-	GI(Protien) :
PubChem	Potency	uM	22.387	VDR	-	GI(Protien) :
PubChem	Potency	uM	35.481	WRN	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	7943.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	12589.300	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	7943.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	10000.000	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	39810.700	KAT2A	-	Target : CHEMBL5501
ChEMBL	Potency	nM	31622.800	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	22387.200	MAPT	-	Target : CHEMBL1293224

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