Tan Lab | DSigDB

Gene Set: D4 : CTD - trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

Collection

D4 : CTD

Chemical Name

trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride ( From PubChem : AY 9944 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
464.299 g/mol	4	2	8.065	False(3/4)

Structure

InChI

InChI=1S/C22H28Cl2N2.2ClH/c23-21-7-3-1-5-19(21)15-25-13-17-9-11-18(12-10-17)14-26-16-20-6-2-4-8-22(20)24;;/h1-8,17-18,25-26H,9-16H2;2*1H

InChIKey

Links

Gene (23 / 29)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ASAH1		D001371
CTD	increases(expression)			ASNS		D001371
CTD	increases(expression)			C10ORF10		D001371
CTD	increases(expression)			FABP1		D001371
CTD	increases(expression)			FNDC4		D001371
CTD	increases(expression)			GDPD3		D001371
CTD	increases(expression)			HPN		D001371
CTD	increases(expression)			IL12A		D001371
CTD	affects(binding)			IL12A		D001371
CTD	affects(binding)			IL12B		D001371
CTD	increases(expression)			IL12B		D001371
CTD	increases(expression)			IL2RA		D001371
CTD	increases(expression)			INHBE		D001371
CTD	increases(expression)			LSS		D001371
CTD	increases(expression)			NR0B2		D001371
CTD	increases(expression)			NUPR1		D001371
CTD	increases(expression)			PHYH		D001371
CTD	increases(expression)			SERPINA3		D001371
CTD	decreases(expression)			SLC2A3		D001371
CTD	decreases(expression)			TAGLN		D001371
CTD	increases(expression)			WIPI1		D001371
PubChem	Potency	uM	0.794	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	5.012	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	2.986	TDP1	-	GI(Protien) :
PubChem	Potency	uM	2.986	TDP1	-	GI(Protien) :

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