Tan Lab | DSigDB

Gene Set: D4 : CTD - Anisomycin

Collection

D4 : CTD

Chemical Name

Anisomycin ( From PubChem : GNF-PF-4325 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
265.305 g/mol	2	5	0.8309	True

Structure

InChI

InChI=1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m0/s1

InChIKey

YKJYKKNCCRKFSL-BFHYXJOUSA-N

Links

Gene (88 / 215)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(phosphorylation)			AGO2		D000841
CTD	decreases(expression)			AHR		D000841
CTD	increases(degradation)			AHR		D000841
CTD	increases(reaction)			AHR		D000841
CTD	increases(phosphorylation)			ATF1		D000841
CTD	affects(cotreatment)			ATF1		D000841
CTD	decreases(reaction)			ATF1		D000841
CTD	increases(phosphorylation)			ATF2		D000841
CTD	affects(binding)			ATF3		D000841
CTD	increases(activity)			ATF3		D000841
CTD	increases(expression)			ATF3		D000841
CTD	increases(reaction)			ATF3		D000841
CTD	increases(expression)			ATF3		D000841
CTD	increases(expression)			BACH2		D000841
CTD	increases(activity)			BID		D000841
CTD	increases(cleavage)			BID		D000841
CTD	increases(activity)			CASP3		D000841
CTD	increases(reaction)			CASP3		D000841
CTD	increases(activity)			CASP3		D000841
CTD	increases(cleavage)			CASP3		D000841
CTD	increases(activity)			CASP6		D000841
CTD	increases(reaction)			CASP6		D000841
CTD	increases(activity)			CASP8		D000841
CTD	increases(activity)			CASP9		D000841
CTD	increases(reaction)			CASP9		D000841
CTD	increases(phosphorylation)			CAV1		D000841
CTD	decreases(reaction)			CAV1		D000841
CTD	decreases(expression)			CCL2		D000841
CTD	decreases(expression)			CCL4		D000841
CTD	decreases(expression)			CCL5		D000841
CTD	increases(expression)			CD55		D000841
CTD	increases(expression)			CD69		D000841
CTD	increases(phosphorylation)			CREB1		D000841
CTD	decreases(reaction)			CREB1		D000841
CTD	increases(expression)			CREBBP		D000841
CTD	affects(binding)			CXCL1		D000841
CTD	increases(activity)			CXCL1		D000841
CTD	increases(expression)			CXCL1		D000841
CTD	increases(reaction)			CXCL1		D000841
CTD	affects(binding)			CXCL8		D000841
CTD	increases(activity)			CXCL8		D000841
CTD	increases(expression)			CXCL8		D000841
CTD	increases(reaction)			CXCL8		D000841
CTD	decreases(expression)			CXCL8		D000841
CTD	affects(cotreatment)			CYP1A1		D000841
CTD	increases(expression)			CYP1A1		D000841
CTD	affects(cotreatment)			CYP2B6		D000841
CTD	increases(expression)			CYP2B6		D000841
CTD	increases(expression)			DDIT3		D000841
CTD	decreases(expression)			DUSP6		D000841
CTD	increases(phosphorylation)			EIF4E		D000841
CTD	decreases(reaction)			EIF4E		D000841
CTD	decreases(reaction)			ELK1		D000841
CTD	increases(phosphorylation)			ELK1		D000841
CTD	increases(expression)			EVI2A		D000841
CTD	increases(localization)			FAS		D000841
CTD	increases(expression)			FOS		D000841
CTD	increases(expression)			FOSB		D000841
CTD	increases(activity)			IGF1		D000841
CTD	increases(reaction)			IGF1		D000841
CTD	increases(phosphorylation)			IGF1		D000841
CTD	increases(expression)			IL1B		D000841
CTD	decreases(expression)			IL6R		D000841
CTD	increases(phosphorylation)			JUN		D000841
CTD	increases(reaction)			JUN		D000841
CTD	increases(expression)			JUN		D000841
CTD	increases(phosphorylation)			JUN		D000841
CTD	increases(expression)			JUND		D000841
CTD	increases(expression)			MAFF		D000841
CTD	decreases(reaction)			MAPK1		D000841
CTD	increases(phosphorylation)			MAPK1		D000841
CTD	increases(activity)			MAPK10		D000841
CTD	decreases(reaction)			MAPK10		D000841
CTD	increases(activity)			MAPK14		D000841
CTD	increases(phosphorylation)			MAPK14		D000841
CTD	decreases(reaction)			MAPK3		D000841
CTD	increases(phosphorylation)			MAPK3		D000841
CTD	increases(activity)			MAPK8		D000841
CTD	increases(reaction)			MAPK8		D000841
CTD	increases(activity)			MAPK8		D000841
CTD	increases(activity)			MAPK8		D000841
CTD	increases(phosphorylation)			MAPK8		D000841
CTD	increases(phosphorylation)			MAPK8		D000841
CTD	decreases(reaction)			MAPK8		D000841
CTD	increases(activity)			MAPK8		D000841
CTD	increases(phosphorylation)			MAPK8		D000841
CTD	increases(reaction)			MAPK8		D000841
CTD	increases(phosphorylation)			MAPK9		D000841
CTD	increases(activity)			MKNK1		D000841
CTD	decreases(reaction)			MKNK1		D000841
CTD	increases(expression)			MRPS30		D000841
CTD	increases(expression)			MYC		D000841
CTD	affects(binding)			NOD2		D000841
CTD	increases(activity)			NOD2		D000841
CTD	increases(expression)			NOD2		D000841
CTD	increases(reaction)			NOD2		D000841
CTD	affects(cotreatment)			NR1I3		D000841
CTD	increases(expression)			NR1I3		D000841
CTD	increases(expression)			PMAIP1		D000841
CTD	increases(expression)			RHOH		D000841
CTD	increases(degradation)			RNY1		D000841
CTD	increases(degradation)			RNY3		D000841
CTD	increases(degradation)			RNY4		D000841
CTD	increases(degradation)			RNY5		D000841
CTD	increases(expression)			RORA		D000841
CTD	increases(phosphorylation)			RXRA		D000841
CTD	increases(phosphorylation)			SRF		D000841
CTD	decreases(reaction)			SRF		D000841
CTD	increases(expression)			TNF		D000841
CTD	decreases(expression)			TNFSF9		D000841
CTD	increases(expression)			TNFSF9		D000841
CTD	increases(expression)			USP30		D000841
CTD	decreases(expression)			VEGFA		D000841
CTD	decreases(reaction)			ZAK		D000841
CTD	increases(activity)			ZAK		D000841
CTD	increases(phosphorylation)			ZAK		D000841
CTD	increases(reaction)			ZAK		D000841
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		HIF1A	-	GI(Protien) :
PubChem	Potency	uM	1.836	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.461	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	1.458	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	Potency	uM	0.082	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.103	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.112	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.016	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.053	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.075	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.206	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	None	uM		ADRB2	-	GI(Protien) :
PubChem	Potency	uM	0.011	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	0.013	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	0.025	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	0.050	ATAD5	-	GI(Protien) :
PubChem	Potency	uM	0.056	ATAD5	-	GI(Protien) :
PubChem	None	uM		BCL2L11	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	IC50_CF-PAF_Mean	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	Potency	uM	0.046	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.116	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	7.308	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	AC50_uM	uM	0.260	PAX8	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	Potency	uM	0.073	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.103	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.224	SMAD3	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.146	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.146	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
ChEMBL	Potency	nM	461.100	NFE2L2	-	Target : CHEMBL1075094
ChEMBL	Potency	nM	115.800	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

gmt, text, Detailed text