Tan Lab | DSigDB

Gene Set: D4 : CTD - Amodiaquine

Collection

D4 : CTD

Chemical Name

Amodiaquine ( From PubChem : AMODIAQUINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
355.861 g/mol	2	3	5.2522	False(3/4)

Structure

InChI

InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23)

InChIKey

Links

Gene (16 / 21)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	affects(expression)		CCND1		D000655
CTD	affects(expression)		CDKN1A		D000655
CTD	decreases(activity)		CTSB		D000655
CTD	decreases(activity)		CTSD		D000655
CTD	decreases(activity)		CTSL		D000655
CTD	increases(activity)		CYP1A1		D000655
CTD	decreases(activity)		CYP1A2		D000655
CTD	decreases(activity)		CYP2C19		D000655
CTD	affects(metabolic processing)		CYP2C8		D000655
CTD	increases(metabolic processing)		CYP2C8		D000655
CTD	affects(cotreatment)		CYP2C8		D000655
CTD	decreases(activity)		CYP2C8		D000655
CTD	decreases(activity)		CYP2C9		D000655
CTD	affects(expression)		E2F1		D000655
CTD	affects(phosphorylation)		RB1		D000655
CTD	affects(expression)		TP53		D000655
CTD	increases(activity)		TP53		D000655
PubChem	None	uM	DRD1	-	GI(Protien) :
PubChem	None	uM	SLC5A7	-	GI(Protien) :
PubChem	None	uM	SMARCA2	-	GI(Protien) :
PubChem	None	uM	SMARCA2	-	GI(Protien) :

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