Tan Lab | DSigDB

Gene Set: D4 : CTD - Allopurinol

Collection

D4 : CTD

Chemical Name

Allopurinol ( From PubChem : ALLOPURINOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Approved	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
136.111 g/mol	2	3	-0.3538	True

Structure

InChI

InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)

InChIKey

Links

Gene (17 / 28)

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Source	Type	Unit	Gene	PMID	Other
CTD	affects(cotreatment)		CCL2		D000493
CTD	decreases(reaction)		CCL2		D000493
CTD	increases(secretion)		CCL2		D000493
CTD	decreases(reaction)		CXCL10		D000493
CTD	increases(expression)		CXCL10		D000493
CTD	increases(expression)		FOS		D000493
CTD	increases(response to substance)		HLA-B		D000493
CTD	decreases(reaction)		HMOX1		D000493
CTD	increases(expression)		HMOX1		D000493
CTD	decreases(reaction)		HMOX1		D000493
CTD	increases(expression)		HMOX1		D000493
CTD	decreases(reaction)		IFNB1		D000493
CTD	increases(expression)		IFNB1		D000493
CTD	decreases(reaction)		MAPK14		D000493
CTD	increases(phosphorylation)		MAPK14		D000493
CTD	decreases(reaction)		MMP9		D000493
CTD	increases(expression)		MMP9		D000493
CTD	increases(transport)		SLC22A7		D000493
CTD	decreases(reaction)		STAT1		D000493
CTD	increases(phosphorylation)		STAT1		D000493
CTD	decreases(activity)		XDH		D000493
PubChem	None	uM	DUSP1	-	GI(Protien) :
ChEMBL	Inhibition	-	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-	CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-	CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-	CYP3A4	-	Target : CHEMBL340

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