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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Acetylmuramyl-Alanyl-Isoglutamine

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Collection	D4 : CTD
Chemical Name	Acetylmuramyl-Alanyl-Isoglutamine ( From PubChem : MURAMYL DIPEPTIDE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 492.478 g/mol 8 15 -2.4522 False(2/4)
Structure
InChI	InChI=1S/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11-,13+,14+,15+,19+/m0/s1
InChIKey	BSOQXXWZTUDTEL-HKQZRCNGSA-N
Links
Gene (22 / 106) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD affects(binding) ATF3 D000119 CTD increases(activity) ATF3 D000119 CTD increases(expression) ATF3 D000119 CTD increases(reaction) ATF3 D000119 CTD affects(binding) ATF3 D000119 CTD affects(localization) ATF3 D000119 CTD increases(activity) ATF3 D000119 CTD increases(reaction) ATF3 D000119 CTD increases(stability) ATF3 D000119 CTD affects(cotreatment) ATF3 D000119 CTD affects(cotreatment) ATF3 D000119 CTD increases(stability) ATF3 D000119 CTD affects(phosphorylation) ATF3 D000119 CTD affects(reaction) ATF3 D000119 CTD increases(activity) B2M D000119 CTD affects(cotreatment) CD40 D000119 CTD increases(expression) CD40 D000119 CTD affects(cotreatment) CD80 D000119 CTD increases(expression) CD80 D000119 CTD affects(cotreatment) CD83 D000119 CTD increases(expression) CD83 D000119 CTD affects(cotreatment) CD86 D000119 CTD increases(expression) CD86 D000119 CTD affects(binding) CXCL1 D000119 CTD increases(activity) CXCL1 D000119 CTD increases(expression) CXCL1 D000119 CTD increases(reaction) CXCL1 D000119 CTD affects(cotreatment) CXCL1 D000119 CTD increases(stability) CXCL1 D000119 CTD affects(reaction) CXCL1 D000119 CTD affects(binding) CXCL8 D000119 CTD increases(activity) CXCL8 D000119 CTD increases(expression) CXCL8 D000119 CTD increases(reaction) CXCL8 D000119 CTD affects(cotreatment) CXCL8 D000119 CTD increases(stability) CXCL8 D000119 CTD affects(cotreatment) CXCL8 D000119 CTD increases(expression) CXCL8 D000119 CTD increases(expression) CXCL8 D000119 CTD increases(secretion) CXCL8 D000119 CTD decreases(reaction) CXCL8 D000119 CTD affects(reaction) CXCL8 D000119 CTD affects(binding) ELAVL1 D000119 CTD affects(localization) ELAVL1 D000119 CTD increases(activity) ELAVL1 D000119 CTD increases(reaction) ELAVL1 D000119 CTD increases(stability) ELAVL1 D000119 CTD affects(cotreatment) ELAVL1 D000119 CTD affects(reaction) ELAVL1 D000119 CTD affects(cotreatment) IFNG D000119 CTD increases(expression) IFNG D000119 CTD affects(binding) IFNG D000119 CTD affects(cotreatment) IFNG D000119 CTD increases(expression) IFNG D000119 CTD increases(reaction) IFNG D000119 CTD affects(cotreatment) IL12A D000119 CTD increases(expression) IL12A D000119 CTD affects(binding) IL12A D000119 CTD affects(binding) IL12A D000119 CTD affects(cotreatment) IL12A D000119 CTD increases(expression) IL12A D000119 CTD increases(reaction) IL12A D000119 CTD increases(secretion) IL12B D000119 CTD affects(binding) IL12B D000119 CTD affects(cotreatment) IL12B D000119 CTD increases(expression) IL12B D000119 CTD affects(binding) IL12B D000119 CTD affects(cotreatment) IL12B D000119 CTD increases(expression) IL12B D000119 CTD increases(reaction) IL12B D000119 CTD affects(cotreatment) IL15 D000119 CTD increases(expression) IL15 D000119 CTD affects(cotreatment) IL1B D000119 CTD increases(secretion) IL1B D000119 CTD affects(binding) IL23A D000119 CTD affects(cotreatment) IL23A D000119 CTD increases(expression) IL23A D000119 CTD increases(secretion) IL6 D000119 CTD increases(phosphorylation) NFKBIA D000119 CTD decreases(reaction) NFKBIA D000119 CTD affects(activity) NOD2 D000119 CTD affects(binding) NOD2 D000119 CTD affects(binding) NOD2 D000119 CTD increases(activity) NOD2 D000119 CTD increases(expression) NOD2 D000119 CTD increases(reaction) NOD2 D000119 CTD affects(localization) NOD2 D000119 CTD increases(stability) NOD2 D000119 CTD affects(cotreatment) NOD2 D000119 CTD affects(phosphorylation) NOD2 D000119 CTD increases(reaction) NOD2 D000119 CTD affects(reaction) NOD2 D000119 CTD decreases(reaction) NOD2 D000119 CTD affects(binding) RELA D000119 CTD affects(cotreatment) RELA D000119 CTD affects(phosphorylation) RELA D000119 CTD increases(activity) RELA D000119 CTD increases(activity) RELA D000119 CTD affects(localization) RELA D000119 CTD increases(phosphorylation) RELA D000119 CTD affects(reaction) RELA D000119 CTD decreases(reaction) RELA D000119 CTD increases(activity) TLR2 D000119 CTD increases(activity) TLR4 D000119 CTD increases(secretion) TNF D000119 ChEMBL Activity - NOD2 - Target : CHEMBL1293266
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