Tan Lab | DSigDB

Gene Set: D4 : CTD - Acetazolamide

Collection

D4 : CTD

Chemical Name

Acetazolamide ( From PubChem : ACETAZOLAMIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
222.245 g/mol	2	8	0.998	True

Structure

InChI

InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)

InChIKey

Links

Gene (11 / 21)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		AQP1		D000086
CTD	affects(binding)		CA1		D000086
CTD	decreases(activity)		CA1		D000086
CTD	decreases(activity)		CA1		D000086
CTD	decreases(activity)		CA1		D000086
CTD	decreases(reaction)		CA1		D000086
CTD	decreases(activity)		CA12		D000086
CTD	affects(binding)		CA2		D000086
CTD	decreases(activity)		CA2		D000086
CTD	decreases(activity)		CA2		D000086
CTD	decreases(activity)		CA2		D000086
CTD	decreases(reaction)		CA2		D000086
CTD	affects(binding)		CA3		D000086
CTD	decreases(activity)		CA3		D000086
CTD	decreases(activity)		CA9		D000086
CTD	increases(activity)		CASP3		D000086
CTD	increases(reaction)		CASP3		D000086
CTD	increases(expression)		UMOD		D000086
ChEMBL	Activity	-	AQP4	-	Target : CHEMBL5964
ChEMBL	Inhibition	-	MMP12	-	Target : CHEMBL4393
ChEMBL	Inhibition	-	MMP2	-	Target : CHEMBL333

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