Tan Lab | DSigDB

Gene Set: D4 : CTD - alizarin

Collection

D4 : CTD

Chemical Name

alizarin ( From PubChem : ALIZARIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
240.211 g/mol	2	4	1.8732	True

Structure

InChI

InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H

InChIKey

RGCKGOZRHPZPFP-UHFFFAOYSA-N

Links

Gene (29 / 40)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			CYP1A1		C010078
CTD	decreases(activity)			CYP1A2		C010078
CTD	decreases(activity)			CYP1B1		C010078
CTD	decreases(activity)			CYP2A6		C010078
CTD	decreases(activity)			CYP2E1		C010078
CTD	affects(binding)			ESR1		C010078
CTD	increases(activity)			ESR1		C010078
CTD	increases(glucuronidation)			UGT1A1		C010078
CTD	increases(glucuronidation)			UGT1A10		C010078
CTD	increases(glucuronidation)			UGT1A7		C010078
CTD	increases(glucuronidation)			UGT1A8		C010078
CTD	increases(glucuronidation)			UGT1A9		C010078
CTD	increases(metabolic processing)			UGT2B15		C010078
PubChem	AhR Potency (uM)	uM	25.115	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	29.849	AHR	-	GI(Protien) :
PubChem	Potency	uM	10.000	ALOX15	-	GI(Protien) :
PubChem	Potency	uM	7.080	CBX1	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP3A4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	26.806	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	26.832	ESR1	-	GI(Protien) :
PubChem	Potency	uM	7.569	FEN1	-	GI(Protien) :
PubChem	Potency	uM	7.943	FEN1	-	GI(Protien) :
PubChem	Potency	uM	28.184	HPGD	-	GI(Protien) :
PubChem	None	uM		KEAP1	-	GI(Protien) :
PubChem	Potency	uM	8.912	MAPT	-	GI(Protien) :
PubChem	None	uM		NFE2L2	-	GI(Protien) :
PubChem	None	uM		PAFAH1B3	-	GI(Protien) :
PubChem	None	uM		PLA2G3	-	GI(Protien) :
PubChem	Potency	uM	75.686	POLH	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		SIX1	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	ALOX15	-	Target : CHEMBL2903
ChEMBL	Potency	nM	31622.800	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	28183.800	HPGD	-	Target : CHEMBL1293255
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	50118.700	KDM4A	-	Target : CHEMBL5896
ChEMBL	Potency	nM	14125.400	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	28183.800	KDM4E	-	Target : CHEMBL1293226
ChEMBL	Potency	nM	8912.500	MAPT	-	Target : CHEMBL1293224

Download gene sets

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