Tan Lab | DSigDB

Gene Set: D4 : CTD - bendamustine

Collection

D4 : CTD

Chemical Name

bendamustine ( From PubChem : BENDAMUSTINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
358.263 g/mol	1	5	3.2646	True

Structure

InChI

InChI=1S/C16H21Cl2N3O2/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23/h5-6,11H,2-4,7-10H2,1H3,(H,22,23)

InChIKey

Links

Gene (14 / 26)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			BIRC2		C001758
CTD	decreases(expression)			BIRC3		C001758
CTD	increases(reaction)			BIRC3		C001758
CTD	increases(activity)			CASP3		C001758
CTD	increases(reaction)			CASP3		C001758
CTD	increases(activity)			CASP6		C001758
CTD	increases(reaction)			CASP6		C001758
CTD	increases(activity)			CASP7		C001758
CTD	increases(reaction)			CASP7		C001758
CTD	increases(activity)			CASP8		C001758
CTD	increases(reaction)			CASP8		C001758
CTD	increases(activity)			CASP9		C001758
CTD	increases(reaction)			CASP9		C001758
CTD	decreases(expression)			DAXX		C001758
CTD	increases(reaction)			DAXX		C001758
CTD	increases(localization)			DIABLO		C001758
CTD	increases(reaction)			DIABLO		C001758
CTD	increases(cleavage)			PARP1		C001758
CTD	decreases(expression)			PAWR		C001758
CTD	increases(reaction)			PAWR		C001758
CTD	increases(expression)			TP53		C001758
CTD	affects(localization)			XIAP		C001758
CTD	decreases(expression)			XIAP		C001758
CTD	decreases(expression)			XIAP		C001758
CTD	increases(reaction)			XIAP		C001758
PubChem	Potency	uM	18.837	TDP1	-	GI(Protien) :

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