Tan Lab | DSigDB

Gene Set: D4 : CTD - trilostane

Collection

D4 : CTD

Chemical Name

trilostane ( From PubChem : TRILOSTANE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
329.433 g/mol	2	4	3.46688	True

Structure

InChI

InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1

InChIKey

KVJXBPDAXMEYOA-CXANFOAXSA-N

Links

Gene (8 / 22)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			FGF9		C009954
CTD	decreases(reaction)			FGF9		C009954
CTD	increases(abundance)			FGF9		C009954
CTD	affects(cotreatment)			FSHB		C009954
CTD	decreases(reaction)			FSHB		C009954
CTD	increases(abundance)			FSHB		C009954
CTD	affects(cotreatment)			IGF1		C009954
CTD	decreases(reaction)			IGF1		C009954
CTD	increases(abundance)			IGF1		C009954
PubChem	Potency-Replicate_1	uM	0.053	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.151	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.265	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.536	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	28.613	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	16.785	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.306	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	22.816	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	23.708	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	29.484	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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