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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide

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Collection	D4 : CTD
Chemical Name	4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide ( From PubChem : DROXINOSTAT )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 243.687 g/mol 2 4 2.7037 True
Structure
InChI	InChI=1S/C11H14ClNO3/c1-8-7-9(12)4-5-10(8)16-6-2-3-11(14)13-15/h4-5,7,15H,2-3,6H2,1H3,(H,13,14)
InChIKey	JHSXDAWGLCZYSM-UHFFFAOYSA-N
Links
Gene (10 / 15) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) CFLAR C554680 CTD increases(degradation) PARP1 C554680 PubChem IC50_Artemis_Mean uM 1.590 DCLRE1C - GI(Protien) : PubChem None uM DCLRE1C - GI(Protien) : PubChem None uM GFER - GI(Protien) : PubChem None uM HDAC3 - GI(Protien) : PubChem Potency uM 20.596 IDH1 - GI(Protien) : PubChem None uM NFKB1 - GI(Protien) : PubChem None uM NR2F2 - GI(Protien) : PubChem None uM NR2F2 - GI(Protien) : PubChem None uM RELA - GI(Protien) : PubChem Potency uM 8.200 TDP1 - GI(Protien) : PubChem Potency uM 8.912 TDP1 - GI(Protien) : PubChem Potency uM 12.589 TDP1 - GI(Protien) : PubChem Potency uM 18.356 TDP1 - GI(Protien) :
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