Tan Lab | DSigDB

Gene Set: D4 : CTD - xylometazoline

Collection

D4 : CTD

Chemical Name

xylometazoline ( From PubChem : XYLOMETAZOLINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Approved	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
244.375 g/mol	1	2	2.9095	True

Structure

InChI

InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)

InChIKey

Links

Gene (8 / 23)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ADRA1A		C009695
CTD	decreases(reaction)			ADRA1A		C009695
CTD	affects(binding)			ADRA1B		C009695
CTD	decreases(reaction)			ADRA1B		C009695
CTD	affects(binding)			ADRA1D		C009695
CTD	decreases(reaction)			ADRA1D		C009695
CTD	affects(binding)			ADRA2A		C009695
CTD	decreases(reaction)			ADRA2A		C009695
CTD	affects(binding)			ADRA2B		C009695
CTD	increases(activity)			ADRA2B		C009695
CTD	increases(abundance)			ADRA2B		C009695
CTD	decreases(reaction)			ADRA2B		C009695
CTD	affects(binding)			ADRA2C		C009695
CTD	decreases(reaction)			ADRA2C		C009695
CTD	decreases(reaction)			SLC22A2		C009695
CTD	increases(uptake)			SLC22A2		C009695
PubChem	Potency	uM	3.981	CYP2D6	-	GI(Protien) :
PubChem	Potency	uM	31.623	CYP2D6	-	GI(Protien) :
PubChem	None	uM		CYP2D6	-	GI(Protien) :
ChEMBL	AC50	nM	3981.070	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	3981.100	CYP2D6	-	Target : CHEMBL289
ChEMBL	Potency	nM	31622.800	CYP2D6	-	Target : CHEMBL289
ChEMBL	AC50	nM	31622.800	CYP2D6	-	Target : CHEMBL289

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