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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

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Collection	D4 : CTD
Chemical Name	6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide ( From PubChem : 49843-98-3 )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 248.708 g/mol 2 2 3.4268 True
Structure
InChI	InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)/t9-/m1/s1
InChIKey	FUZYTVDVLBBXDL-SECBINFHSA-N
Links
Gene (15 / 57) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) CASP3 C550547 CTD increases(activity) CASP3 C550547 CTD increases(reaction) CASP3 C550547 CTD decreases(reaction) CASP7 C550547 CTD increases(activity) CASP7 C550547 CTD increases(reaction) CASP7 C550547 CTD decreases(activity) FBXO32 C550547 CTD decreases(expression) FBXO32 C550547 CTD decreases(reaction) GCK C550547 CTD increases(expression) GCK C550547 CTD increases(reaction) GCK C550547 CTD decreases(reaction) IL1B C550547 CTD increases(activity) IL1B C550547 CTD increases(expression) IL1B C550547 CTD increases(reaction) IL1B C550547 CTD decreases(activity) IL1B C550547 CTD decreases(reaction) INS C550547 CTD increases(reaction) INS C550547 CTD increases(secretion) INS C550547 CTD decreases(expression) MIR34A C550547 CTD decreases(reaction) MMP1 C550547 CTD increases(activity) MMP1 C550547 CTD increases(expression) MMP1 C550547 CTD increases(reaction) MMP1 C550547 CTD decreases(activity) MMP1 C550547 CTD decreases(activity) MMP3 C550547 CTD increases(expression) MMP3 C550547 CTD increases(reaction) MMP3 C550547 CTD decreases(reaction) PARP1 C550547 CTD increases(cleavage) PARP1 C550547 CTD increases(reaction) PARP1 C550547 CTD decreases(reaction) PDX1 C550547 CTD increases(expression) PDX1 C550547 CTD increases(reaction) PDX1 C550547 CTD decreases(reaction) SIRT1 C550547 CTD increases(activity) SIRT1 C550547 CTD increases(expression) SIRT1 C550547 CTD decreases(reaction) SIRT1 C550547 CTD increases(reaction) SIRT1 C550547 CTD increases(secretion) SIRT1 C550547 CTD increases(expression) SIRT1 C550547 CTD decreases(activity) SIRT1 C550547 CTD decreases(activity) SIRT1 C550547 CTD increases(reaction) SIRT1 C550547 CTD decreases(activity) SIRT1 C550547 CTD decreases(expression) SIRT1 C550547 CTD increases(expression) SIRT1 C550547 CTD decreases(reaction) SIRT1 C550547 CTD decreases(reaction) SLC2A2 C550547 CTD increases(expression) SLC2A2 C550547 CTD increases(reaction) SLC2A2 C550547 CTD decreases(reaction) TFAM C550547 CTD increases(expression) TFAM C550547 CTD increases(reaction) TFAM C550547 CTD increases(acetylation) TP53 C550547 CTD decreases(reaction) TP53 C550547 ChEMBL Inhibition - SIRT1 - Target : CHEMBL4506
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