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Gene Set: D4 : CTD - N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

Collection D4 : CTD
Chemical Name N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide ( From PubChem : IVACAFTOR )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
392.491 g/mol 3 4 5.154 False(3/4)
Structure
InChI InChI=1S/C24H28N2O3/c1-23(2,3)16-11-17(24(4,5)6)20(27)12-19(16)26-22(29)15-13-25-18-10-8-7-9-14(18)21(15)28/h7-13,27H,1-6H3,(H,25,28)(H,26,29)
InChIKey PURKAOJPTOLRMP-UHFFFAOYSA-N
Links

Gene (1 / 5)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(activity)CFTR
C545203
CTDincreases(activity)CFTR
C545203
CTDaffects(transport)CFTR
C545203
CTDincreases(activity)CFTR
C545203
CTDincreases(secretion)CFTR
C545203
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