Tan Lab | DSigDB

Gene Set: D4 : CTD - bis(4-hydroxyphenyl)sulfone

Collection

D4 : CTD

Chemical Name

bis(4-hydroxyphenyl)sulfone ( From PubChem : 4,4'-SULFONYLDIPHENOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
250.27 g/mol	2	4	3.0114	True

Structure

InChI

InChI=1S/C12H10O4S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8,13-14H

InChIKey

Links

Gene (7 / 23)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			AR		C543008
CTD	increases(activity)			AR		C543008
CTD	decreases(activity)			AR		C543008
CTD	affects(binding)			ESR1		C543008
CTD	increases(activity)			ESR1		C543008
CTD	increases(activity)			ESR1		C543008
CTD	affects(cotreatment)			ESR1		C543008
CTD	increases(activity)			ESR1		C543008
CTD	affects(cotreatment)			ESR2		C543008
CTD	increases(activity)			ESR2		C543008
CTD	increases(activity)			ESR2		C543008
CTD	increases(expression)			GSTA4		C543008
CTD	affects(activity)			MAPK1		C543008
CTD	affects(activity)			MAPK3		C543008
CTD	affects(binding)			NR1I2		C543008
CTD	decreases(activity)			NR1I2		C543008
PubChem	Potency-Replicate_1	uM	1.933	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.881	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.106	ESR1	-	GI(Protien) :
PubChem	Potency	uM	14.125	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.583	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	16.094	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.541	ESR1	-	GI(Protien) :

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