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Gene Set: D4 : CTD - INCB018424


Collection D4 : CTD
Chemical Name INCB018424 ( From PubChem : RUXOLITINIB )
FDA NPC WHO Indian Australia China Traditional
Herbal
Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight
Hydrogen Bond
Donor Count
Hydrogen Bond
Acceptor Count
cLogP Lipinski Rule
306.365 g/mol 1 5 3.46638 True
Structure
InChI InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChIKey HFNKQEVNSGCOJV-OAHLLOKOSA-N
Links

Gene (7 / 13)


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Source Type Unit Value Gene PMID Assay Other
CTDdecreases(expression)CDH1
C540383
CTDdecreases(reaction)CDH1
C540383
CTDdecreases(reaction)CDH2
C540383
CTDincreases(expression)CDH2
C540383
CTDdecreases(reaction)ITGB1
C540383
CTDincreases(expression)ITGB1
C540383
CTDdecreases(reaction)JAK1
C540383
CTDincreases(phosphorylation)JAK1
C540383
CTDdecreases(activity)JAK1
C540383
CTDdecreases(activity)JAK2
C540383
CTDdecreases(reaction)STAT3
C540383
CTDincreases(phosphorylation)STAT3
C540383
PubChem PotencyuM2.442YES1GI(Protien) :
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