Tan Lab | DSigDB

Gene Set: D4 : CTD - tetramethrin

Collection

D4 : CTD

Chemical Name

tetramethrin ( From PubChem : TETRAMETHRIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
331.406 g/mol	0	5	2.9028	True

Structure

InChI

InChI=1S/C19H25NO4/c1-11(2)9-14-15(19(14,3)4)18(23)24-10-20-16(21)12-7-5-6-8-13(12)17(20)22/h9,14-15H,5-8,10H2,1-4H3/t14-,15+/m1/s1

InChIKey

Links

Gene (11 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			AR		C009424
CTD	increases(activity)			AR		C009424
CTD	decreases(expression)			AR		C009424
CTD	decreases(reaction)			CES2		C009424
CTD	increases(activity)			CES2		C009424
CTD	increases(metabolic processing)			CES2		C009424
CTD	increases(metabolic processing)			CYP3A4		C009424
CTD	decreases(expression)			FOLH1		C009424
CTD	increases(expression)			KLK3		C009424
CTD	decreases(expression)			NKX3-1		C009424
CTD	decreases(reaction)			NR1I2		C009424
CTD	increases(activity)			NR1I2		C009424
CTD	increases(expression)			TMPRSS2		C009424
PubChem	Potency-Replicate_1	uM	43.641	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	48.966	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	48.966	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	54.941	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	33.489	HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.882	PPARG	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :

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