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Gene Set: D4 : CTD - MK-0524

Collection D4 : CTD
Chemical Name MK-0524 ( From PubChem : LAROPIPRANT )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
435.896 g/mol 1 5 5.4709 False(3/4)
Structure
InChI InChI=1S/C21H19ClFNO4S/c1-29(27,28)18-10-15(23)9-17-16-7-4-13(8-19(25)26)20(16)24(21(17)18)11-12-2-5-14(22)6-3-12/h2-3,5-6,9-10,13H,4,7-8,11H2,1H3,(H,25,26)/t13-/m1/s1
InChIKey NXFFJDQHYLNEJK-CYBMUJFWSA-N
Links

Gene (7 / 11)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDincreases(metabolic processing)CYP2C9
C518174
CTDincreases(metabolic processing)CYP3A4
C518174
CTDaffects(binding)PTGDR
C518174
CTDdecreases(activity)PTGDR
C518174
CTDaffects(binding)PTGDR
C518174
CTDdecreases(activity)PTGDR
C518174
CTDdecreases(response to substance)PTGDR
C518174
CTDincreases(glucuronidation)UGT1A1
C518174
CTDincreases(glucuronidation)UGT1A3
C518174
CTDincreases(glucuronidation)UGT1A9
C518174
CTDincreases(glucuronidation)UGT2B7
C518174
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